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Here we describe the natural history of ventricular hypertrophy and fibrosis in the transgenic (mRen2)27 rat a monogenetic model which has a high tissue expression of the murine renin transgene, and ...

Cardiovascular Research, Original Article, Jill E. Bishop, Linda A. Kiernan, Hugh E. Montgomery, Peter Gohlke, Jean R. McEwan

Date : 01/07/2000 Item size : 254674 bytes

KeywordsAntihypertensive agentsHeart rate (variability)HemodynamicsHypertensionHypertrophyVentricular function 1 Introductory remarks Left ventricular hypertrophy (LVH) was recognized as early as in ...

Cardiovascular Research, Update review, P.A. van Zwieten

Date : 01/01/2000 Item size : 366202 bytes

Methods: 2K-1C hypertension was induced in male SpragueDawley rats weighing 100125 g by placing a silver clip (internal diameter 0.25 mm) around the left renal artery through a flank ...

Cardiovascular Research, Original Article, Liliana G. Bianciotti, Adolfo J. de Bold

Date : 01/03/2001 Item size : 226147 bytes

Some details are given on the three studies to date which point to remodelling of subcutaneous resistance arteries as an independent predictor of cardiovascular risk in hypertensive ...

Cardiovascular Research, Review, François Feihl, Lucas Liaudet, Bernard I. Levy, Bernard Waeber

Date : 01/05/2008 Item size : 516786 bytes

Any increase in cardiac chamber radius (r) and/or pressure (p) will result in a proportional increase in total wall tension (T) according to the ideal Laplace formula, T = pr. The true load on the ...

Cardiovascular Research, Editorial, Elieser Kaplinsky

Date : 01/12/2003 Item size : 157716 bytes

After its first entry into the scientific stage [1] the deletion polymorphism of the Angiotensin Converting Enzyme presented cardiovascular researchers with a grateful opportunity to explore genetic ...

Cardiovascular Research, Editorial, Yigal M Pinto, Wiek H van Gilst

Date : 01/07/1999 Item size : 145611 bytes

Abstract Aims We investigated the effects of iptakalim, a new ATP-sensitive potassium channel (KATP) opener providing endothelial protection, on the progression of cardiac hypertrophy to failure in a ...

Cardiovascular Research, Original Article, Shan Gao, Chao-Liang Long, Ru-Huan Wang, Hai Wang

Date : 01/08/2009

Methods: CK-deficient mice (CK KO) were examined by cardiac magnetic resonance imaging (MRI) to determine left ventricular volumes, ejection fraction, and mass: ten wild-type (WT), 6 mitochondrial CK ...

Cardiovascular Research, Research Article, Matthias Nahrendorf, Matthias Spindler, Kai Hu, Lisa Bauer, Oliver Ritter, Peter Nordbeck, Thomas Quaschning, Karl-Heinz Hiller, Julie Wallis, Georg Ertl, ...

Date : 01/02/2005

Patients with normal or increased (>125 g/m2 in males and >110 g/m2 in females) left ventricular mass were considered to have concentric remodeling or concentric left ventricular hypertrophy if their ...

Cardiovascular Research, Original Article, Francesco Perticone, Raffaele Maio, Carmela Cosco, Roberto Ceravolo, Saverio Iacopino, Massimo Chello, Pasquale Mastroroberto, Donatella Tramontano, Pier L ...

Date : 01/07/1999

Methods and Results: Rats were studied 12 weeks after banding of the ascending aorta (LVH, n=20) that resulted in a 1.7-fold increase in left ventricular (LV) to body weight ratio. [...]as compared ...

Cardiovascular Research, Original Article, Michael Pfeifer, Günter Bruckschlegel, Stephan R Holmer, Martin Paul, A.J.Günter Riegger, Heribert Schunkert

Date : 01/04/1998