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Abstract Several pathologies of the cardiovascular system are associated with an augmented production of nitric oxide and/or superoxide-derived oxidants and/or alteration in the antioxidant ...

Cardiovascular Research, Review, Gonzalo Peluffo, Rafael Radi

Date : 15/07/2007 Item size : 511451 bytes

The review article from Frueh et al.8 embraces this complexity and describes the current challenges of large data sets and the application of systems biology in the exploration of the effects of ...

Cardiovascular Research, Editorial, Paul C. Evans, Brenda R. Kwak

Date : 15/07/2013 Item size : 192536 bytes

[...]pharmacological strategies aimed at the prevention and treatment of acute cardiovascular disease thus far mainly focus on the reduction of atherosclerotic burden (e.g. by preventative strategies ...

Cardiovascular Research, Editorial, Marcel Levi, Erik Stroes

Date : 01/06/2008 Item size : 156179 bytes

Abstract Leukotrienes (LTs) derived from 5-lipoxygenase (5-LO) activity are most widely known for their actions during acute inflammation and asthma. 5-LO/LT pathway involvement in cardiovascular ...

Cardiovascular Research, SPOTLIGHT REVIEWS, Daniel Poeckel, Colin D. Funk

Date : 01/05/2010 Item size : 563066 bytes

In addition to their lipid-lowering effects, one central biological action of statins is their ability to ameliorate the impaired bioavailability of NO.1 Mechanistically, this occurs through ...

Cardiovascular Research, Editorial, Stephan H. Schirmer, Christian M. Werner, Ulrich Laufs, Michael Böhm

Date : 01/06/2012 Item size : 181712 bytes

The endothelium modulates vascular tone, regulates local cellular growth and the deposition of the extracellular matrix, protects the vessel from the potentially harmful consequences of substances ...

Cardiovascular Research, Review, Kwang Kon Koh

Date : 01/09/2002 Item size : 558962 bytes

CCR5 and its ligands were expressed in normal and diseased coronary artery and saphenous vein and localized to medial and intimal smooth muscle, endothelial, and inflammatory cells. Conclusions Our ...

Cardiovascular Research, Vascular biology, Janet J. Maguire, Katie L. Jones, Rhoda E. Kuc, Murray C.H. Clarke, Martin R. Bennett, Anthony P. Davenport

Date : 01/03/2014

Abstract Aims Previous studies from our laboratory have demonstrated that testosterone increases coronary smooth muscle protein kinase C delta (PKCδ) both in vivo and in vitro and inhibits ...

Cardiovascular Research, Original Article, Darla L. Tharp, Isabelle Masseau, Jan Ivey, Venkataseshu K. Ganjam, Douglas K. Bowles

Date : 01/04/2009

Abstract Objective: Postmenopausal estrogen replacement therapy lowers the incidence of cardiovascular disease, suggesting that estrogens support cardiovascular function. Channel activity was ...

Cardiovascular Research, Original Article, Richard E White, Guichun Han, Melissa Maunz, Christiana Dimitropoulou, Abdalla M El-Mowafy, Robert S Barlow, John D Catravas, Connie Snead, Gerald O ...

Date : 15/02/2002

Vascular dysfunction has been linked to cardiovascular disease and aging, although most research has focused on endothelium-dependent vasodilator dysfunction. Results: There was an age-associated ...

Cardiovascular Research, Original Article, Anthony J. Donato, Lisa A. Lesniewski, Michael D. Delp

Date : 01/05/2005