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Abstract Cardiomyocytes are terminally differentiated cells and thus do not have the ability to dilute damaged proteins and organelles by cell division. [...]proteolytic and recycling systems within ...

Cardiovascular Research, REVIEWS: FOCUS ON THE CALPAIN FAMILY IN THE CARDIOVASCULAR SYSTEM, Osamu Yamaguchi, Manabu Taneike, Kinya Otsu

Date : 01/10/2012 Item size : 446563 bytes

Whether cardiac mitochondria have an innate capacity to temporally self-modulate their membrane potential as a possible adaptive mechanism in the context of cardiac ischemia and early reperfusion is ...

Cardiovascular Research, Review, Michael N. Sack

Date : 01/11/2006 Item size : 474381 bytes

Abstract Aims Proteasome inhibitors are a novel class of anticancer agents that induce tumour cell death via endoplasmic reticulum (ER) stress. Since ER stress is involved in the development of ...

Cardiovascular Research, Original Article, Hai Ying Fu, Tetsuo Minamino, Osamu Tsukamoto, Tamaki Sawada, Mitsutoshi Asai, Hisakazu Kato, Yoshihiro Asano, Masashi Fujita, Seiji Takashima, Masatsugu ...

Date : 01/09/2008 Item size : 291190 bytes

Abstract Objective: Nitric oxide signaling pathways are of central importance in both the maintenance of vascular homeostasis and the progression of vascular disease. Since smooth muscle cell ...

Cardiovascular Research, Original Article, Shiow L Pan, Jih H Guh, Ya L Chang, Sheng C Kuo, Fang Y Lee, Che M Teng

Date : 01/01/2004 Item size : 246942 bytes

Owing to their dependence on Ca2+, calpains have attracted much attention as modulators implicated in a wide variety of biological phenomena including proliferation, cell migration, differentiation, ...

Cardiovascular Research, Editorial, Javier Inserte

Date : 01/10/2012 Item size : 179731 bytes

Abstract Aims It has been shown that sarcoplasmic reticulum calcium ATPase (SERCA) plays a critical role in reperfusion injury. [...]ischaemic post-conditioning (PoCo) results in protein kinase G ...

Cardiovascular Research, Cardiac biology and remodelling, Javier Inserte, Víctor Hernando, Marisol Ruiz-Meana, Marcos Poncelas-Nozal, Celia Fernández, Luis Agulló, Carmem Sartorio, Úrsula ...

Date : 01/09/2014 Item size : 366352 bytes

Abstract Objectives: Loss of cardiac cells and the anatomical or functional remodeling of intercellular coupling occur under several pathological conditions. Treatment of the cultured myocytes at ...

Cardiovascular Research, Original Article, Kenji Yasui, Kenji Kada, Mayumi Hojo, Jong-Kook Lee, Kaichiro Kamiya, Junji Toyama, Tobias Opthof, Itsuo Kodama

Date : 01/10/2000 Item size : 273879 bytes

The concept of cardiac remodelling was initially created to describe the changes in the anatomy of the left ventricle that occur following myocardial infarction.1 Today myocardial remodelling is used ...

Cardiovascular Research, Editorial, Javier Díez, Georg Ertl

Date : 15/02/2009 Item size : 201037 bytes

Introduction MicroRNAs (miRNAs or miRs) have become increasingly recognized as major regulators of various physiological processes.1 Recently, modulation of miR activity in the heart has been ...

Cardiovascular Research, Cardiac biology and remodelling, Yaoping Tang, Yongchao Wang, Kyoung-mi Park, Qiuping Hu, Jian-peng Teoh, Zuzana Broskova, Punithavathi Ranganathan, Calpurnia Jayakumar, Jie ...

Date : 01/06/2015 Item size : 470749 bytes

Ang II increased ERK phosphorylation, which was inhibited by addition of the AT1 receptor-specific antagonist CV11974, but enhanced by addition of the AT2 receptor-specific antagonist PD123319, ...

Cardiovascular Research, Original Article, Tai-Xing Cui, Hironori Nakagami, Masaru Iwai, Yuko Takeda, Tetsuya Shiuchi, Laurent Daviet, Clara Nahmias, Masatsugu Horiuchi

Date : 01/03/2001 Item size : 291255 bytes