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Ehjcardiovascrec

Methods and results Stabilization of myocardial HIF-1 was achieved by pharmacological inhibition of prolyl hydroxylase (PHD) domain-containing enzyme using GSK360A or using cardiac-specific ablation ...

Cardiovascular Research, Ong, Sang-Ging, Lee, Won Hee, Theodorou, Louise, Kodo, Kazuki, Lim, Shiang Y., Shukla, Deepa H., Briston, Thomas, Kiriakidis, Serafim, Ashcroft, Margaret, Davidson, Sean M., ...

Date : 01/10/2014
Ehjcardiovascrec

Time for primary review 18 days 1 Introduction Ischemic preconditioning (IPC), first described by Murry and co-workers in 1986 [1] as an effective endogenous protective phenomenon whereby exposure to ...

Cardiovascular Research, Lim, Shiang Y., Davidson, Sean M., Hausenloy, Derek J., Yellon, Derek M.

Date : 01/08/2007 Item size : 224487 bytes
Ehjcardiovascrec

Abstract Aims It has been suggested that mitochondrial reactive oxygen species (ROS), Akt and Erk1/2 and more recently the mitochondrial permeability transition pore (mPTP) may act as mediators of ...

Cardiovascular Research, Hausenloy, Derek J., Lim, Shiang Y., Ong, Sang-Ging, Davidson, Sean M., Yellon, Derek M.

Date : 01/10/2010
Ehjcardiovascrec

Abstract Aims In the heart, a period of ischaemia followed by reperfusion evokes powerful cytosolic Ca2+ oscillations that can cause lethal cell injury. Restoration of blood supply is essential to ...

Cardiovascular Research, Davidson, Sean M., Foote, Kirsty, Kunuthur, Suma, Gosain, Raj, Tan, Noah, Tyser, Richard, Zhao, Yong Juan, Graeff, Richard, Ganesan, A., Duchen, Michael R., Patel, Sandip, ...

Date : 01/12/2015 Item size : 401036 bytes
Ehjcardiovascrec

Abstract Although the specific roles of nitric oxide (NO) in the heart in general and on cardiac mitochondria in particular remain controversial, it is now clear that both endogenous and exogenous ...

Cardiovascular Research, Davidson, Sean M., Duchen, Michael R.

Date : 01/07/2006
Ehjcardiovascrec

Abstract Although the specific roles of nitric oxide (NO) in the heart in general and on cardiac mitochondria in particular remain controversial, it is now clear that both endogenous and exogenous ...

Cardiovascular Research, Davidson, Sean M., Duchen, Michael R.

Date : 01/07/2006 Item size : 535041 bytes
Ehjcardiovascrec

Abstract Aims In the heart, a period of ischaemia followed by reperfusion evokes powerful cytosolic Ca2+ oscillations that can cause lethal cell injury. Restoration of blood supply is essential to ...

Cardiovascular Research, Davidson, Sean M., Foote, Kirsty, Kunuthur, Suma, Gosain, Raj, Tan, Noah, Tyser, Richard, Zhao, Yong Juan, Graeff, Richard, Ganesan, A., Duchen, Michael R., Patel, Sandip, ...

Date : 01/12/2015 Item size : 400430 bytes