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Introduction Nearly twenty years after its initial description, the phenomenon of ischemic preconditioning, whereby episodes of intermittent sublethal ischemia and reperfusion confer resistance ...

Cardiovascular Research, Review, Derek J. Hausenloy, Derek M. Yellon

Date : 01/05/2006 Item size : 525135 bytes

[...]recent evidence indicates that the contribution of mitochondria to cell injury goes well beyond their role as death executors through the opening of mitochondrial permeability transition pore ...

Cardiovascular Research, EDITORIAL: FOCUS ON MITOCHONDRIA IN CARDIAC DISEASE, Derek J. Hausenloy, Marisol Ruiz-Meana

Date : 01/10/2010 Item size : 156284 bytes

The research article which attracted our attention was by two pioneers in MPTP research, Fabio Di Lisa and Paulo Bernardi at the University of Padova.1 In their experimental study, they had ...

Cardiovascular Research, EDITORIALS: SPOTLIGHT ON LANDMARK PAPERS IN, Derek J. Hausenloy, Helen L. Maddock, Gary F. Baxter, Derek M. Yellon

Date : 01/11/2012 Item size : 280986 bytes

The mechanisms of protection by postconditioning include: formation and release of several autacoids and cytokines; maintained acidosis during early reperfusion; activation of protein kinases; ...

Cardiovascular Research, Review, Michel Ovize, Gary F. Baxter, Fabio Di Lisa, Péter Ferdinandy, David Garcia-Dorado, Derek J. Hausenloy, Gerd Heusch, Jakob Vinten-Johansen, Derek M. Yellon, Rainer ...

Date : 01/08/2010

KeywordsIschemiaMitochondriaReperfusionPreconditioningTime for primary review 18 days 1 Introduction Ischemic preconditioning (IPC), first described by Murry and co-workers in 1986 [1] as an ...

Cardiovascular Research, Original Article, Shiang Y. Lim, Sean M. Davidson, Derek J. Hausenloy, Derek M. Yellon

Date : 01/08/2007

During reperfusion, calcium overloading, elevated levels of reactive oxygen species (ROS), and abrupt restoration of pH, all act in concert to induce mitochondrial dysfunction leading to the ...

Cardiovascular Research, Cardiac biology and remodelling, Sang-Ging Ong, Won Hee Lee, Louise Theodorou, Kazuki Kodo, Shiang Y. Lim, Deepa H. Shukla, Thomas Briston, Serafim Kiriakidis, Margaret ...

Date : 01/10/2014