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Ehjcardiovascrec

Abstract Objective: The cytokine cardiotrophin-1 (CT-1) has previously been shown to protect cultured cardiocytes from cell death induced by serum removal or hypoxia when administered prior to the ...

Cardiovascular Research, Brar, Bhawanjit K, Stephanou, Anastasis, Liao, Zhihong, O'Leary, Rhona M, Pennica, Diane, Yellon, Derek M, Latchman, David S

Date : 01/08/2001
Ehjcardiovascrec

Abstract Background: Recent studies have postulated that mitochondrial ATP-sensitive potassium (mitoKATP) channel activation may modulate mitochondrial function with the resultant induction of a ...

Cardiovascular Research, Minners, Jan, van den Bos, Ewout J, Yellon, Derek M, Schwalb, Herzl, Opie, Lionel H, Sack, Michael N

Date : 01/07/2000
Ehjcardiovascrec

Abstract Objective: The opening of the mitochondrial permeability transition pore (mPTP) in the first few minutes of post-ischaemic reperfusion is a critical determinant of reperfusion-induced cell ...

Cardiovascular Research, Hausenloy, Derek J, Duchen, Michael R, Yellon, Derek M

Date : 01/12/2003
Ehjcardiovascrec

Introduction The phosphatidylinositol 3-OH kinase (PI3K)Akt [1,2], and the Rafmitogen activated protein kinase (MAPK), extracellular signal-regulated kinase (RafMEK1/2Erk1/2) cascades [3], are ...

Cardiovascular Research, Hausenloy, Derek J, Mocanu, Mihaela M, Yellon, Derek M

Date : 01/08/2004 Item size : 272820 bytes
Ehjcardiovascrec

The phenomenon of ischaemic preconditioning, in which a period of sublethal ischemia can profoundly protect the cell from subsequent lethal ischemic insult, has without doubt been responsible for an ...

Cardiovascular Research, Yellon, Derek M, Downey, James M

Date : 15/08/2002 Item size : 205674 bytes
Ehjcardiovascrec

The phenomenon of ischaemic preconditioning, in which a period of sublethal ischemia can profoundly protect the cell from subsequent lethal ischemic insult, has without doubt been responsible for an ...

Cardiovascular Research, Yellon, Derek M, Downey, James M

Date : 15/08/2002 Item size : 179121 bytes
Ehjcardiovascrec

Abstract Background: Recent studies have postulated that mitochondrial ATP-sensitive potassium (mitoKATP) channel activation may modulate mitochondrial function with the resultant induction of a ...

Cardiovascular Research, Minners, Jan, van den Bos, Ewout J, Yellon, Derek M, Schwalb, Herzl, Opie, Lionel H, Sack, Michael N

Date : 01/07/2000
Ehjcardiovascrec

Therapeutic strategies that target and attenuate reperfusion-induced cell death may provide novel pharmacological agents, which can be used as an adjunct to current reperfusion therapy, to limit ...

Cardiovascular Research, Hausenloy, Derek J, Yellon, Derek M

Date : 15/02/2004 Item size : 559838 bytes
Ehjcardiovascrec

Abstract Objective: The cytokine cardiotrophin-1 (CT-1) has previously been shown to protect cultured cardiocytes from cell death induced by serum removal or hypoxia when administered prior to the ...

Cardiovascular Research, Brar, Bhawanjit K, Stephanou, Anastasis, Liao, Zhihong, O'Leary, Rhona M, Pennica, Diane, Yellon, Derek M, Latchman, David S

Date : 01/08/2001
Ehjcardiovascrec

Abstract Objective: The opening of the mitochondrial permeability transition pore (mPTP) in the first few minutes of post-ischaemic reperfusion is a critical determinant of reperfusion-induced cell ...

Cardiovascular Research, Hausenloy, Derek J, Duchen, Michael R, Yellon, Derek M

Date : 01/12/2003 Item size : 243929 bytes