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Abstract Macrophages play a key role in atherosclerotic plaque destabilization and rupture. [...]macrophages are phagocytic cells and thus have an important additional role in scavenging of modified ...

Cardiovascular Research, Review, Dorien M. Schrijvers, Guido R.Y. De Meyer, Arnold G. Herman, Wim Martinet

Date : 01/02/2007 Item size : 443225 bytes

Specifically, we address the role of vascular smooth muscle cell death, how this may be regulated at the molecular level and whether any of these molecular mediators will provide targets for ...

Cardiovascular Research, Review, Nicola J. McCarthy, Martin Bennett

Date : 01/02/2000 Item size : 446583 bytes

Abstract Objective: Nitric oxide signaling pathways are of central importance in both the maintenance of vascular homeostasis and the progression of vascular disease. Since smooth muscle cell ...

Cardiovascular Research, Original Article, Shiow L Pan, Jih H Guh, Ya L Chang, Sheng C Kuo, Fang Y Lee, Che M Teng

Date : 01/01/2004 Item size : 246942 bytes

Abstract Objective: Instability of coronary atheroma leads to the onset of acute coronary syndromes including myocardial infarction and death, as well as to the progression of the arteriosclerotic ...

Cardiovascular Research, Original Article, Gerhard Bauriedel, Randolph Hutter, Ulrich Welsch, Roland Bach, Horst Sievert, Berndt Lüderitz

Date : 01/02/1999

Apoptosis may be an important mode of cell death in heart failure but it must be demonstrated by multiple criteria and not just TUNEL staining alone. Previously, we and others have demonstrated that ...

Cardiovascular Research, Original Article, Michiel W.M. Knaapen, Michael J. Davies, Martine De Bie, Aldwyn J. Haven, Wim Martinet, Mark M. Kockx

Date : 01/08/2001

Gap junctions enable the cytoplasm of individual cells to communicate directly and allow exchange of nutrients, ions, metabolites and small molecules up to about 1000 Da [1]. [30] suggest that a ...

Cardiovascular Research, Editorial, G. Taimor

Date : 01/10/2000

Apoptosis can be initiated or controlled by developmental and environmental factors such as DNA damage, viral infection, cellular damage and loss of cellcell or cellsubstrate contact; it is also ...

Cardiovascular Research, Review, Mojgan Rezvani, J.David Barrans, Ken-Shwo Dai, Choong-Chin Liew

Date : 01/02/2000

[...]it is controversial whether TUNEL-positive cardiomyocytes in infarcted myocardium are all apoptotic. Apoptosis research since 1994, in relation to myocardial ischaemia and infarction, is ...

Cardiovascular Research, Review, Hiroyuki Yaoita, Kazuei Ogawa, Kazuhira Maehara, Yukio Maruyama

Date : 01/02/2000

Introduction The incidence of ischaemic heart disease (IHD) and sequelae such as myocardial infarction (MI) is lower in pre-menopausal women than in age-matched men. [...]women who are on hormone ...

Cardiovascular Research, Original Article, Han Liu, Ali Pedram, Jin Kyung Kim

Date : 01/01/2011

Abstract Aims Humanin (HN) is a 24-amino acid peptide that has been shown to have an anti-apoptotic function against neuronal cell death caused by Alzheimer's disease. Methods and results HN ...

Cardiovascular Research, Original Article, Adi R. Bachar, Lea Scheffer, Andreas S. Schroeder, Hiromi K. Nakamura, Laura J. Cobb, Yun K. Oh, Lilach O. Lerman, Richard E. Pagano, Pinchas Cohen, Amir ...

Date : 01/11/2010