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Ehjcardiovascrec

Abstract Aims Proteasome inhibitors are a novel class of anticancer agents that induce tumour cell death via endoplasmic reticulum (ER) stress. Since ER stress is involved in the development of ...

Cardiovascular Research, Original Article, Hai Ying Fu, Tetsuo Minamino, Osamu Tsukamoto, Tamaki Sawada, Mitsutoshi Asai, Hisakazu Kato, Yoshihiro Asano, Masashi Fujita, Seiji Takashima, Masatsugu ...

Date : 01/09/2008 Item size : 291190 bytes
Ehjcardiovascrec

Death of terminally differentiated cardiomyocytes is implicated in the development of various cardiac pathologies.1,2 For example, following myocardial infarction, cell death in the infarct zone may ...

Cardiovascular Research, Editorial, Angela Clerk, Peter H. Sugden

Date : 01/01/2010 Item size : 166370 bytes
Ehjcardiovascrec

The importance of apoptosis in heart failure has been recognized for over a decade, while other forms of programmed cell death have more recently been appreciated, and their pathophysiological roles ...

Cardiovascular Research, Review, Gerald W. Dorn

Date : 15/02/2009 Item size : 499993 bytes
Ehjcardiovascrec

Caspase-dependent signalling is important during heart morphogenesis and is later silenced in post-mitotic cardiomyocytes Cell death implying apoptotic-like DNA damage occurs during embryonic heart ...

Cardiovascular Research, VIEWPOINT EDITORIAL, Daniel Sanchis, Marta Llovera, Manel Ballester, Joan X. Comella

Date : 01/02/2008
Ehjcardiovascrec

[...]the so-called Ca2+ paradox (hypercontracture and death of cardiomyocytes occurring upon restoration of Ca2+ after a Ca2+-free perfusion period) was meant to be a first cellular model of ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, David Garcia-Dorado, Marisol Ruiz-Meana, Javier Inserte, Antonio Rodriguez-Sinovas, Hans Michael Piper

Date : 01/05/2012
Ehjcardiovascrec

Introduction The number of individuals with diabetes is expected to reach 300 million by the year 2025.1 Individuals with diabetes have an increased risk for developing heart failure.2 Moreover, ...

Cardiovascular Research, Original Article, Craig W. Younce, Kangkai Wang, Pappachan E. Kolattukudy

Date : 01/09/2010
Ehjcardiovascrec

[1] dealing with the action of growth hormone on left ventricle remodeling after myocardial infarction in rats, the authors have concluded that growth hormone enhanced cardiomyocyte hypertrophy and ...

Cardiovascular Research, Letter to the Editor, Jiri T Beranek

Date : 01/07/1999
Ehjcardiovascrec

[...]it is controversial whether TUNEL-positive cardiomyocytes in infarcted myocardium are all apoptotic. Apoptosis research since 1994, in relation to myocardial ischaemia and infarction, is ...

Cardiovascular Research, Review, Hiroyuki Yaoita, Kazuei Ogawa, Kazuhira Maehara, Yukio Maruyama

Date : 01/02/2000
Ehjcardiovascrec

Results Compared to non-failing SHR, failing SHR exhibited enhanced myocardial cell death (p<0.01) demonstrated by the increase in Bax/Bcl-2 ratio, caspase-3 activation and poly (ADP-ribose) ...

Cardiovascular Research, Original Article, Natalia López, Nerea Varo, Javier Díez, María Antonia Fortuño

Date : 01/08/2007
Ehjcardiovascrec

Death of terminally differentiated cardiomyocytes is implicated in the development of various cardiac pathologies.1,2 For example, following myocardial infarction, cell death in the infarct zone may ...

Cardiovascular Research, Clerk, Angela, Sugden, Peter H.

Date : 01/01/2010 Item size : 131433 bytes