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Abstract Objective: The cytokine cardiotrophin-1 (CT-1) has previously been shown to protect cultured cardiocytes from cell death induced by serum removal or hypoxia when administered prior to the ...

Cardiovascular Research, Original Article, Bhawanjit K Brar, Anastasis Stephanou, Zhihong Liao, Rhona M O'Leary, Diane Pennica, Derek M Yellon, David S Latchman

Date : 01/08/2001 Item size : 297331 bytes

Abstract Objective: Nitric oxide signaling pathways are of central importance in both the maintenance of vascular homeostasis and the progression of vascular disease. Since smooth muscle cell ...

Cardiovascular Research, Original Article, Shiow L Pan, Jih H Guh, Ya L Chang, Sheng C Kuo, Fang Y Lee, Che M Teng

Date : 01/01/2004 Item size : 246942 bytes

Abstract Objectives: Loss of cardiac cells and the anatomical or functional remodeling of intercellular coupling occur under several pathological conditions. Treatment of the cultured myocytes at ...

Cardiovascular Research, Original Article, Kenji Yasui, Kenji Kada, Mayumi Hojo, Jong-Kook Lee, Kaichiro Kamiya, Junji Toyama, Tobias Opthof, Itsuo Kodama

Date : 01/10/2000 Item size : 273879 bytes

Dysfunction and β-cell death normally follows an immune attack.1,2 As a result, there is decreased insulin synthesis and secretion.1 Compared to T1D, Type 2 diabetes (T2D) is the major form of ...

Cardiovascular Research, TOPICAL REVIEWS, Prasanth Puthanveetil, Andrea Wan, Brian Rodrigues

Date : 01/03/2013 Item size : 582544 bytes

[...]strategies have been developed to promote cell survival and cell differentiation.11,12 Since the pioneering work of Murry et al.,2 preconditioning is considered to be the most potent and ...

Cardiovascular Research, EDITORIALS: SPOTLIGHT ON LANDMARK PAPERS IN, Zeeshan Pasha, Muhammad Ashraf

Date : 01/11/2012 Item size : 238166 bytes

Abstract Aims The aim of this study was to take a combination of animal and cell culture approaches to examine the individual responses of vascular cells to varying inflammatory factors in order to ...

Cardiovascular Research, Original Article, Chetan P. Hans, Mourad Zerfaoui, Amarjit S. Naura, Andrew Catling, A. Hamid Boulares

Date : 01/06/2008 Item size : 230010 bytes

The section opens with a paper by Saraste and Pulkki [1] that reviews the current knowledge on the molecular mechanisms of apoptosis as they relate to morphologic hallmarks and their implications for ...

Cardiovascular Research, Editorial, Marcel Borgers, Liisa-Maria Voipio-Pulkki, Seigo Izumo

Date : 01/02/2000 Item size : 187734 bytes

Remarkably, as the ΔΨm dissipates, i.e. under hypoxic conditions or when H+ influx follows an alternative route not coupled to energy production, mitochondria can act as ATP consumers by ...

Cardiovascular Research, REVIEWS: FOCUS ON MITOCHONDRIA IN CARDIAC DISEASE, Marisol Ruiz-Meana, Celia Fernandez-Sanz, David Garcia-Dorado

Date : 01/10/2010 Item size : 637391 bytes

Methods: We cultured adult mouse cardiac myocytes from wildtype and SphK1-null mice (deletion of exons 36) and measured cell viability by trypan blue exclusion. [...]the absence of the Sphk1 gene ...

Cardiovascular Research, Original Article, Rong Tao, Jianqing Zhang, Donald A. Vessey, Norman Honbo, Joel S. Karliner

Date : 01/04/2007 Item size : 275991 bytes

The MAS is a biochemical system that translocates reducing power from the cytosol into the mitochondria, thus linking glycolysis with the electron transport chain.11 Although previous studies have ...

Cardiovascular Research, EDITORIAL: FOCUS ON MITOCHONDRIA IN CARDIAC DISEASE, Alejandra González-Loyola, Ignasi Barba

Date : 01/11/2010