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Abstract In the last decade, apoptosis (or programmed cell death) has become appreciated as an important process in the development of the cardiovascular system. [...]apoptosis contributes to the ...

Cardiovascular Research, Review, Waander L van Heerde, Saskia Robert-Offerman, Ewald Dumont, Leo Hofstra, Pieter A Doevendans, Jos F.M Smits, Mat J.A.P Daemen, Chris P.M Reutelingsperger

Date : 01/02/2000 Item size : 493731 bytes

Death of terminally differentiated cardiomyocytes is implicated in the development of various cardiac pathologies.1,2 For example, following myocardial infarction, cell death in the infarct zone may ...

Cardiovascular Research, Editorial, Angela Clerk, Peter H. Sugden

Date : 01/01/2010 Item size : 166370 bytes

Abstract Although the specific roles of nitric oxide (NO) in the heart in general and on cardiac mitochondria in particular remain controversial, it is now clear that both endogenous and exogenous ...

Cardiovascular Research, Review, Sean M. Davidson, Michael R. Duchen

Date : 01/07/2006 Item size : 551284 bytes

Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death Abstract Objective: The signaling pathways ...

Cardiovascular Research, Original Article, Frank Jung, Judith Haendeler, Christine Goebel, Andreas M. Zeiher, Stefanie Dimmeler

Date : 01/10/2000

Abstract Aims Exposure to high glucose (HG) stimulates reactive oxygen species (ROS) production by NADPH oxidase in cardiomyocytes, but the underlying mechanism remains elusive. HG exposure ...

Cardiovascular Research, Original Article, Magali Balteau, Nicolas Tajeddine, Carole de Meester, Audrey Ginion, Christine Des Rosiers, Nathan R. Brady, Caroline Sommereyns, Sandrine Horman, ...

Date : 01/11/2011

Abstract Aims In the heart, a period of ischaemia followed by reperfusion evokes powerful cytosolic Ca2+ oscillations that can cause lethal cell injury. Restoration of blood supply is essential to ...

Cardiovascular Research, Cardiac biology and remodelling, Sean M. Davidson, Kirsty Foote, Suma Kunuthur, Raj Gosain, Noah Tan, Richard Tyser, Yong Juan Zhao, Richard Graeff, A. Ganesan, Michael R. ...

Date : 01/12/2015

Conclusion: Our results demonstrated for the first time that l-arginine administered at different time points during ischemia/reperfusion exerted different effects on post-ischemic myocardial injury, ...

Cardiovascular Research, Original Article, Feng Liang, Erhe Gao, Ling Tao, Huirong Liu, Yan Qu, Theodore A Christopher, Bernard L Lopez, Xin L Ma

Date : 01/06/2004

[...]the barrier segregating flowing blood from metabolizing tissue is a complex structure composed of the endothelium with its associated basement membrane and surface glycocalyx, as well as the ...

Cardiovascular Research, Editorial, Virginia H. Huxley

Date : 01/08/2013

Smooth muscle cell (SMC)-driven neointimal hyperplasia is a key mechanism that reduces the long-term benefit of vascular interventions such as stenting, balloon angioplasty, and by-pass ...

Cardiovascular Research, Editorial, Jens W. Fischer

Date : 01/02/2010

The best-characterized inflammasome is the nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain containing 3 (NLRP3; also known as NALP3 and cryopyrin) inflammasome, ...

Cardiovascular Research, Editorial, Masafumi Takahashi

Date : 01/07/2013