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[...]strategies have been developed to promote cell survival and cell differentiation.11,12 Since the pioneering work of Murry et al.,2 preconditioning is considered to be the most potent and ...

Cardiovascular Research, EDITORIALS: SPOTLIGHT ON LANDMARK PAPERS IN, Zeeshan Pasha, Muhammad Ashraf

Date : 01/11/2012 Item size : 238166 bytes

Abstract Objective: Proliferation of vascular smooth muscle cells (VSMC) is an important event in atherogenesis, in-stent restenosis and late vein-graft failure. Introduction Proliferation of ...

Cardiovascular Research, Original Article, Mark Bond, Graciela B. Sala-Newby, Yih-Jer Wu, Andrew C. Newby

Date : 01/01/2006 Item size : 267682 bytes

With the initiation of ischaemia, as oxygen levels fall, ATP levels fall in the affected cells, and as minutes go by, ion pumps in the cell membranes stop. The severity of hypoxia determines whether ...

Cardiovascular Research, Editorial, Eileen M. Denovan-Wright, R. William Currie

Date : 01/11/2011 Item size : 148615 bytes

Abstract Objectives Septic shock and sequential multiple organ failure remain the cause of death in septic patients. Synthetic small interfering RNAs (siRNAs) specifically suppress gene expression ...

Cardiovascular Research, Original Article, Naoyuki Matsuda, Yasuo Takano, Shun-ichiro Kageyama, Noboru Hatakeyama, Kiyoshi Shakunaga, Isao Kitajima, Mitsuaki Yamazaki, Yuichi Hattori

Date : 01/10/2007 Item size : 307264 bytes

Abstract Markers of increased oxidative stress are known to be elevated following acute myocardial infarction and in the context of chronic left ventricular hypertrophy or heart failure, and their ...

Cardiovascular Research, Review, Colin E. Murdoch, Min Zhang, Alison C. Cave, Ajay M. Shah

Date : 15/07/2006

The aged SHR model of decompensated heart failure has provided insight into the role of the extracellular matrix in the transition to failure, and can be useful to further investigate the mechanistic ...

Cardiovascular Research, Review, Marvin O. Boluyt, Oscar H.L. Bing

Date : 01/05/2000

Abstract Aims Although a substantial role for 5 adenosine monophosphate-activated protein kinase (AMPK) has been established in regulating cardiac metabolism, a less studied action of AMPK is its ...

Cardiovascular Research, Original Article, Girish Kewalramani, Prasanth Puthanveetil, Fang Wang, Min Suk Kim, Sylvia Deppe, Ashraf Abrahani, Dan S. Luciani, James D. Johnson, Brian Rodrigues

Date : 01/10/2009

Introduction MicroRNAs (miRNAs) are small non-coding molecules that negatively regulate gene expression via translational repression or mRNA degradation.13 Recent studies have shown that miRNAs ...

Cardiovascular Research, Original Article, Yumei Ye, Zhaoyong Hu, Yu Lin, Congfang Zhang, Jose R. Perez-Polo

Date : 01/08/2010

The most widely studied PC is ischemic PC, which can be achieved in the heart with a variety of stress responses including cyclic episodes of short durations of ischemia/reperfusion [6], ...

Cardiovascular Research, Review, Dipak K. Das, Nilanjana Maulik

Date : 01/05/2006

The review highlights metabolic imprints and energetic aspects of programmed cell survival, programmed cell death, and of necrosis. When moderate, ischemia results in a coordinated cellular response ...

Cardiovascular Research, Review, Christophe Depre, Heinrich Taegtmeyer

Date : 01/02/2000