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Ehjcardiovascrec

Consistent with a role in promoting necroptosis, adenoviral overexpression of RIP3 in neonatal rat cardiomyocytes and stimulation with TNF-α induced the formation of a complex of RIP1 and ...

Cardiovascular Research, Cardiac biology and remodelling, Mark Luedde, Matthias Lutz, Natalie Carter, Justyna Sosna, Christoph Jacoby, Mihael Vucur, Jérémie Gautheron, Christoph Roderburg, ...

Date : 15/07/2014 Item size : 330213 bytes
Ehjcardiovascrec

Mitochondria have been implicated in the loss of cells in various cardiac pathologies, including ischaemia/reperfusion injury, cardiomyopathy, and congestive heart failure. The strategic positioning ...

Cardiovascular Research, Review, Åsa B. Gustafsson, Roberta A. Gottlieb

Date : 15/01/2008 Item size : 598788 bytes
Ehjcardiovascrec

Therapeutic strategies that target and attenuate reperfusion-induced cell death may provide novel pharmacological agents, which can be used as an adjunct to current reperfusion therapy, to limit ...

Cardiovascular Research, Review, Derek J Hausenloy, Derek M Yellon

Date : 15/02/2004 Item size : 565898 bytes
Ehjcardiovascrec

Abstract In the last decade, apoptosis (or programmed cell death) has become appreciated as an important process in the development of the cardiovascular system. [...]apoptosis contributes to the ...

Cardiovascular Research, Review, Waander L van Heerde, Saskia Robert-Offerman, Ewald Dumont, Leo Hofstra, Pieter A Doevendans, Jos F.M Smits, Mat J.A.P Daemen, Chris P.M Reutelingsperger

Date : 01/02/2000 Item size : 493731 bytes
Ehjcardiovascrec

[...]compensatory mechanisms included LV hypertrophy, LV chamber dilation, and enhanced and sustained activity of the sympathetic nervous system and reninangiotensin system [36]. The notion that ...

Cardiovascular Research, Review, Hani N. Sabbah

Date : 01/02/2000 Item size : 422731 bytes
Ehjcardiovascrec

Owing to their dependence on Ca2+, calpains have attracted much attention as modulators implicated in a wide variety of biological phenomena including proliferation, cell migration, differentiation, ...

Cardiovascular Research, Editorial, Javier Inserte

Date : 01/10/2012 Item size : 179731 bytes
Ehjcardiovascrec

The concept of cardiac remodelling was initially created to describe the changes in the anatomy of the left ventricle that occur following myocardial infarction.1 Today myocardial remodelling is used ...

Cardiovascular Research, Editorial, Javier Díez, Georg Ertl

Date : 15/02/2009 Item size : 201037 bytes
Ehjcardiovascrec

[...]strategies have been developed to promote cell survival and cell differentiation.11,12 Since the pioneering work of Murry et al.,2 preconditioning is considered to be the most potent and ...

Cardiovascular Research, EDITORIALS: SPOTLIGHT ON LANDMARK PAPERS IN, Zeeshan Pasha, Muhammad Ashraf

Date : 01/11/2012 Item size : 238166 bytes
Ehjcardiovascrec

Evidence for the existence of apoptosis in the human heart has been reported in various cardiac diseases, including ischemic and non-ischemic heart failure, myocardial infarction and ...

Cardiovascular Research, Review, Giora Z. Feuerstein, Peter R. Young

Date : 01/02/2000 Item size : 352446 bytes
Ehjcardiovascrec

Ischemia/reperfusion-induced apoptosis: connecting nitric oxide and cell cycle regulators [...]serum stimulation of neonatal, terminally-differentiated cardiomyocytes, similarly to what happens in ...

Cardiovascular Research, Editorial, Carla Pignatti, Claudio Stefanelli

Date : 01/08/2003 Item size : 210601 bytes