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Ehjcardiovascrec

Methods: The effect of several concentrations of KB-R7943 added at reperfusion was studied in Fura-2 loaded quiescent cardiomyocytes submitted to 40 min of simulated ischemia (NaCN 2 mM, pH 6.4), and ...

Cardiovascular Research, Original Article, Javier Inserte, David Garcia-Dorado, Marisol Ruiz-Meana, Ferran Padilla, José A Barrabés, Pilar Pina, Luis Agulló, Hans Michael Piper, Jordi ...

Date : 01/09/2002 Item size : 271773 bytes
Ehjcardiovascrec

Introduction Nearly twenty years after its initial description, the phenomenon of ischemic preconditioning, whereby episodes of intermittent sublethal ischemia and reperfusion confer resistance ...

Cardiovascular Research, Review, Derek J. Hausenloy, Derek M. Yellon

Date : 01/05/2006 Item size : 525135 bytes
Ehjcardiovascrec

Introduction Since the protection afforded by brief episodes of ischemia against cell death induced by subsequent prolonged ischemia and reperfusion was originally described in 1986 [1], an enormous ...

Cardiovascular Research, Review, David Garcia-Dorado, Antonio Rodriguez-Sinovas, Marisol Ruiz-Meana, Javier Inserte, Luis Agulló, Alberto Cabestrero

Date : 01/05/2006 Item size : 490461 bytes
Ehjcardiovascrec

Acute coronary occlusion resulting in myocardial infarction is the main mechanism by which coronary artery disease reduces survival and leads to deterioration of the quality of life, and the extent ...

Cardiovascular Research, Editorial, David Garcı́a-Dorado

Date : 15/02/2004 Item size : 147067 bytes
Ehjcardiovascrec

Despite its overall beneficial effect, experimental myocardial reperfusion was associated with prominent arrhythmias, enzyme release, and other adverse phenomena that were grouped under the imprecise ...

Cardiovascular Research, Viewpoint Editorial, David Garcia-Dorado, Hans Michael Piper

Date : 01/01/2006 Item size : 186761 bytes
Ehjcardiovascrec

Methods and results Pigs were submitted to 40 min of coronary occlusion followed by reperfusion, and received (i) no treatment, (ii) one of the following treatments: RIC (5 min ischemia/5 min ...

Cardiovascular Research, Original Article, Juan José Alburquerque-Béjar, Ignasi Barba, Javier Inserte, Elisabet Miró-Casas, Marisol Ruiz-Meana, Marcos Poncelas, Úrsula Vilardosa, Laura ...

Date : 15/07/2015 Item size : 344631 bytes
Ehjcardiovascrec

The research article which attracted our attention was by two pioneers in MPTP research, Fabio Di Lisa and Paulo Bernardi at the University of Padova.1 In their experimental study, they had ...

Cardiovascular Research, EDITORIALS: SPOTLIGHT ON LANDMARK PAPERS IN, Derek J. Hausenloy, Helen L. Maddock, Gary F. Baxter, Derek M. Yellon

Date : 01/11/2012 Item size : 280986 bytes
Ehjcardiovascrec

Methods and results The effect of acidic perfusion on reperfusion injury was studied in isolated rat hearts submitted to 40 min of ischaemia and 30 min of reperfusion, and its effect on the ...

Cardiovascular Research, ORIGINALS, Javier Inserte, Ignasi Barba, Víctor Hernando, Arancha Abellán, Marisol Ruiz-Meana, Antonio Rodríguez-Sinovas, David Garcia-Dorado

Date : 01/03/2008
Ehjcardiovascrec

[...]the so-called Ca2+ paradox (hypercontracture and death of cardiomyocytes occurring upon restoration of Ca2+ after a Ca2+-free perfusion period) was meant to be a first cellular model of ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, David Garcia-Dorado, Marisol Ruiz-Meana, Javier Inserte, Antonio Rodriguez-Sinovas, Hans Michael Piper

Date : 01/05/2012
Ehjcardiovascrec

KeywordsIschemiaMitochondriaReperfusionPreconditioningTime for primary review 18 days 1 Introduction Ischemic preconditioning (IPC), first described by Murry and co-workers in 1986 [1] as an ...

Cardiovascular Research, Original Article, Shiang Y. Lim, Sean M. Davidson, Derek J. Hausenloy, Derek M. Yellon

Date : 01/08/2007