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Ehjcardiovascrec

Introduction Fibroblasts are numerous within the healthy myocardium and are essential in the regulation of the extracellular matrix to maintain correct functioning of the heart.1,2 In cardiac ...

Cardiovascular Research, Original Article, James E. Cartledge, Christopher Kane, Priyanthi Dias, Meron Tesfom, Lucy Clarke, Benjamin Mckee, Samha Al Ayoubi, Adrian Chester, Magdi H. Yacoub, Patrizia ...

Date : 01/03/2015 Item size : 339824 bytes
Ehjcardiovascrec

Through the metabolic breakdown of ingested nutrients, subsequent production of the electron carriers NADH and FADH2 in the citric acid cycle and the transfer of electrons through the electron ...

Cardiovascular Research, Review, Alexander W. Lohman, Marie Billaud, Brant E. Isakson

Date : 01/08/2012 Item size : 637634 bytes
Ehjcardiovascrec

[...]understanding of the exact role of TGF-β signaling in the infarcted and remodeling heart has been hampered by the complex and unusual biology of TGF-β activation and by the diversity of ...

Cardiovascular Research, Review, Marcin Bujak, Nikolaos G. Frangogiannis

Date : 01/05/2007 Item size : 448075 bytes
Ehjcardiovascrec

The development and structure of blood vessels are highly adapted to haemodynamic forces, such as shear stress, cyclic stretch, and circumferential wall stress, generated by the conductance of ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON BIOMECHANICAL FACTORS IN CARDIOVASCULAR DISEASE, Peter Neth, Maliheh Nazari-Jahantigh, Andreas Schober, Christian Weber

Date : 15/07/2013 Item size : 558042 bytes
Ehjcardiovascrec

Introduction Around 30% of the cells within the heart are cardiomyocytes, whereas the other 70% comprise endothelial cells (EC), fibroblasts, smooth muscle cells, and immune cells.1 Physical ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON HETEROCELLULAR SIGNALLING AND CROSSTALK IN THE HEART IN ISCHAEMIA AND HEART FAILURE, Min Zhang, Ajay M. Shah

Date : 01/05/2014 Item size : 621988 bytes
Ehjcardiovascrec

Abstract Cardiac hypertrophy and fibrosis are two closely related adaptive response mechanisms of the myocardium to mechanical, metabolic, and genetic stress that finally contribute to the ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON HETEROCELLULAR SIGNALLING AND CROSSTALK IN THE HEART IN ISCHAEMIA AND HEART FAILURE, Janika Viereck, Claudia Bang, Ariana Foinquinos, Thomas ...

Date : 01/05/2014 Item size : 769285 bytes
Ehjcardiovascrec

The principal kinin peptides involved in the acute regulation of cardiovascular function during normal physiology are bradykinin (BK) and Lys-BK which produce their effects via activation of B2 ...

Cardiovascular Research, Review, Peter G. McLean, Mauro Perretti, Amrita Ahluwalia

Date : 01/11/2000 Item size : 683659 bytes
Ehjcardiovascrec

Methods: Poly A+ RNA was prepared from neonatal (2-day) and adult (42-day) cardiac myocytes and whole ventricular tissue and mRNA expression determined by reverse transcription-polymerase chain ...

Cardiovascular Research, Original Article, Caryn J McGill, Gavin Brooks

Date : 01/05/1997 Item size : 190838 bytes
Ehjcardiovascrec

For purposes of macromolecule transport, multiple caveolae can form trans-endothelial channels and vesiculo-vacuolar organelles and/or cavicles.3 In terms of EC function, caveolae are important ...

Cardiovascular Research, SPOTLIGHT REVIEWS, John H. Chidlow, William C. Sessa

Date : 01/05/2010 Item size : 474381 bytes
Ehjcardiovascrec

Endothelial injury can give rise to endothelial dysfunction in which the profile of mediators released by endothelial cells is altered. Introduction The vascular endothelium is not an inert cellular ...

Cardiovascular Research, Review, Arántzazu Alfranca, Miguel A. Iñiguez, Manuel Fresno, Juan Miguel Redondo

Date : 01/06/2006 Item size : 488960 bytes