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Ehjcardiovascrec

Pulmonary arterial hypertension (PAH) is a severe condition characterized by a progressive increase in pulmonary vascular resistance leading to right ventricular failure and death. An activation of ...

Cardiovascular Research, Review, Nazzareno Galié, Alessandra Manes, Angelo Branzi

Date : 01/02/2004 Item size : 434770 bytes
Ehjcardiovascrec

Pharmacological studies have established that a blockade of the RAS at the level of the angiotensin-converting enzyme (ACE) or the AT1-receptor ameliorates the remodeling process of the heart and ...

Cardiovascular Research, Review, Kai C Wollert, Helmut Drexler

Date : 01/09/1999 Item size : 591071 bytes
Ehjcardiovascrec

Abstract The G protein-coupled receptor kinases (GRKs) participate with arrestins in the regulation and signal propagation of multiple G protein-coupled receptors (GPCR) of key physiological and ...

Cardiovascular Research, Review, Petronila Penela, Cristina Murga, Catalina Ribas, Antonio S. Tutor, Sandra Peregrín, Federico Mayor

Date : 01/01/2006 Item size : 407122 bytes
Ehjcardiovascrec

[...]the lack of definitive SMC lineage-tracing studies in the context of atherosclerosis, and difficulties in identifying phenotypically modulated SMCs within lesions that have down-regulated ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON SMOOTH MUSCLE CELLS AND VASCULAR DISEASES, Delphine Gomez, Gary K. Owens

Date : 15/07/2012 Item size : 440953 bytes
Ehjcardiovascrec

ETA receptors on vascular smooth muscle mediate vasoconstriction,1 as well as mitogenesis,2 reactive oxygen species production, and adhesion molecule expression,3,4 while those on leucocytes mediate ...

Cardiovascular Research, Original Article, Nicholas S. Kirkby, Karolina M. Duthie, Eileen Miller, Yuri V. Kotelevtsev, Alan J. Bagnall, David J. Webb, Patrick W.F. Hadoke

Date : 01/07/2012 Item size : 284129 bytes
Ehjcardiovascrec

High-density lipoproteins (HDLs) have captured the imagination of scientists and physicians from virtually the time they were originally described, but especially after the cholesterol carried in HDL ...

Cardiovascular Research, Editorial, Daniel J. Rader

Date : 01/08/2014 Item size : 380769 bytes
Ehjcardiovascrec

Abstract The transforming growth factor type-β (TGF-β) superfamily of ligands, receptors, binding proteins and ligand traps together plays a key role in the maintenance of normal blood vessel ...

Cardiovascular Research, Review, David J. Grainger

Date : 01/05/2007 Item size : 469966 bytes
Ehjcardiovascrec

Abstract Hereditary hemorrhagic telangiectasia (HHT) is a vascular disorder in humans which has been mapped to two genes, endoglin and activin receptor-like kinase-1 (ALK-1) both of which mediate ...

Cardiovascular Research, Review, Sander van den Driesche, Christine L. Mummery, Cornelius J.J. Westermann

Date : 01/04/2003
Ehjcardiovascrec

Human relevance of pre-clinical studies in stem cell therapy: systematic review and meta-analysis of large animal models of ischaemic heart disease Methods and results Random-effects meta-analysis ...

Cardiovascular Research, Original Article, Tycho I.G. van der Spoel, Sanne J. Jansen of Lorkeers, Pierfrancesco Agostoni, Eric van Belle, Mariann Gyöngyösi, Joost P.G. Sluijter, Maarten J. ...

Date : 01/09/2011
Ehjcardiovascrec

Pulmonary arterial hypertension (PAH) is a severe condition characterized by a progressive increase in pulmonary vascular resistance leading to right ventricular failure and death. An activation of ...

Cardiovascular Research, Galié, Nazzareno, Manes, Alessandra, Branzi, Angelo

Date : 01/02/2004 Item size : 406124 bytes