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Ehjcardiovascrec

[...]understanding of the exact role of TGF-β signaling in the infarcted and remodeling heart has been hampered by the complex and unusual biology of TGF-β activation and by the diversity of ...

Cardiovascular Research, Review, Marcin Bujak, Nikolaos G. Frangogiannis

Date : 01/05/2007 Item size : 448075 bytes
Ehjcardiovascrec

Abstract Atherosclerosis is considered to be a form of chronic inflammation governed by a complex network of inter- and intra-cellular signaling pathways. Introduction Atherosclerosis, an underlying ...

Cardiovascular Research, Review, Elizabeth J. Harvey, Dipak P. Ramji

Date : 01/07/2005 Item size : 433326 bytes
Ehjcardiovascrec

Abstract A fundamental feature of any immune response is the movement of leucocytes from one site in the body to another to provide effector functions. [...]elucidating the molecular mechanisms ...

Cardiovascular Research, SPOTLIGHT REVIEWS, Connie H.Y. Wong, Bryan Heit, Paul Kubes

Date : 01/05/2010 Item size : 487398 bytes
Ehjcardiovascrec

In addition to Th9 or Th2 cells, mast cells, eosinophils, innate lymphoid cells (ILCs), and NKT cells have been shown to be sources for this cytokine.3 The differentiation of Th9 cells is dependent ...

Cardiovascular Research, Editorial, Soraya Taleb, Alain Tedgui

Date : 01/06/2015 Item size : 226804 bytes
Ehjcardiovascrec

Elucidation of the functional denominators that link immune activation and derailed cholesterol metabolism may facilitate the development of novel therapeutic strategies to treat ...

Cardiovascular Research, Editorial, Saskia C.A. de Jager, Gerard Pasterkamp

Date : 01/10/2013 Item size : 176096 bytes
Ehjcardiovascrec

HDL particles display a wide spectrum of atheroprotective activities, which include effluxing cellular cholesterol, diminishing cellular death, decreasing vascular constriction, reducing inflammatory ...

Cardiovascular Research, TOPICAL REVIEWS: SPOTLIGHT ON HDL BIOLOGY: NEW INSIGHTS IN METABOLISM, FUNCTION, AND TRANSLATION, Anatol Kontush

Date : 01/08/2014 Item size : 730909 bytes
Ehjcardiovascrec

The best-characterized inflammasome is the nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain containing 3 (NLRP3; also known as NALP3 and cryopyrin) inflammasome, ...

Cardiovascular Research, Editorial, Masafumi Takahashi

Date : 01/07/2013
Ehjcardiovascrec

Effective targets for these pharmacologic agents include: (a) inhibiting the release or accumulation of proinflammatory mediators, (b) altering neutrophil or endothelial cell activation and (c) ...

Cardiovascular Research, Review, James E. Jordan, Zhi-Qing Zhao, Jakob Vinten-Johansen

Date : 01/09/1999
Ehjcardiovascrec

Among CD4+T cells, Th 1 cells have been shown to exert proatherogenic effects, whereas regulatory T cells (Treg) display atheroprotective properties and the role of Th2 and Th17 cells remains ...

Cardiovascular Research, Taleb, Soraya, Tedgui, Alain

Date : 01/06/2015
Ehjcardiovascrec

Effective targets for these pharmacologic agents include: (a) inhibiting the release or accumulation of proinflammatory mediators, (b) altering neutrophil or endothelial cell activation and (c) ...

Cardiovascular Research, Jordan, James E., Zhao, Zhi-Qing, Vinten-Johansen, Jakob

Date : 01/09/1999