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Ehjcardiovascrec

[...]understanding of the exact role of TGF-β signaling in the infarcted and remodeling heart has been hampered by the complex and unusual biology of TGF-β activation and by the diversity of ...

Cardiovascular Research, Review, Marcin Bujak, Nikolaos G. Frangogiannis

Date : 01/05/2007 Item size : 448075 bytes
Ehjcardiovascrec

Pharmacological studies have established that a blockade of the RAS at the level of the angiotensin-converting enzyme (ACE) or the AT1-receptor ameliorates the remodeling process of the heart and ...

Cardiovascular Research, Review, Kai C Wollert, Helmut Drexler

Date : 01/09/1999 Item size : 591071 bytes
Ehjcardiovascrec

Abstract In the last decade, apoptosis (or programmed cell death) has become appreciated as an important process in the development of the cardiovascular system. [...]apoptosis contributes to the ...

Cardiovascular Research, Review, Waander L van Heerde, Saskia Robert-Offerman, Ewald Dumont, Leo Hofstra, Pieter A Doevendans, Jos F.M Smits, Mat J.A.P Daemen, Chris P.M Reutelingsperger

Date : 01/02/2000 Item size : 493731 bytes
Ehjcardiovascrec

[...]AT2 receptor stimulation inhibits growth and promotes apoptosis, an important mechanism during development and tissue remodeling. [...]ANG stimulates the release of nitric oxide (NO)/cGMP via ...

Cardiovascular Research, Review, Olaf Jöhren, Andreas Dendorfer, Peter Dominiak

Date : 01/06/2004 Item size : 423872 bytes
Ehjcardiovascrec

Here, we sum up current knowledge on STAT3-mediated intra- and intercellular communication within the heterogeneous cellular network of the myocardium to co-ordinate complex biological processes and ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON HETEROCELLULAR SIGNALLING AND CROSSTALK IN THE HEART IN ISCHAEMIA AND HEART FAILURE, Arash Haghikia, Melanie Ricke-Hoch, Britta Stapel, Irina ...

Date : 01/05/2014 Item size : 482791 bytes
Ehjcardiovascrec

The large number of the extracellular signals and the intracellular pathways evoked represent potential drug targets. [...]the definition of the network of heterotypic cellular interactions in heart ...

Cardiovascular Research, Editorial, Emilio Hirsch, Ryozo Nagai, Thomas Thum

Date : 01/05/2014 Item size : 169401 bytes
Ehjcardiovascrec

Abstract Objective The paradigm that cardiac myocytes are non-proliferating and terminally differentiated cells has recently been challenged by several studies reporting the ability of bone ...

Cardiovascular Research, Original Article, Helge Möllmann, Holger M. Nef, Sawa Kostin, Christof von Kalle, Ingo Pilz, Michael Weber, Jutta Schaper, Christian W. Hamm, Albrecht Elsässer

Date : 01/09/2006 Item size : 300680 bytes
Ehjcardiovascrec

Recently, the resident macrophage is considered to have vital functions in the maintenance of tissues and homeostasis in many organs, including brain, liver, adipose tissue, lymphatic tissue, and ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON HETEROCELLULAR SIGNALLING AND CROSSTALK IN THE HEART IN ISCHAEMIA AND HEART FAILURE, Katsuhito Fujiu, Jack Wang, Ryozo Nagai

Date : 01/05/2014 Item size : 404798 bytes
Ehjcardiovascrec

Anemia also occurs quite frequently in patients with chronic heart failure, and may be an independent risk factor for adverse outcomes [1]. In a report in this issue of Cardiovascular Research, Tada ...

Cardiovascular Research, Editorial, Sean M. Davidson, Derek M. Yellon

Date : 01/08/2006 Item size : 188483 bytes
Ehjcardiovascrec

[...]research focused on FGF-2 has revealed an important place for this protein in cardiac cells in health and disease. Despite its name, FGF-2 is now known to modulate numerous cellular functions ...

Cardiovascular Research, Review, Karen A. Detillieux, Farah Sheikh, Elissavet Kardami, Peter A. Cattini

Date : 01/01/2003 Item size : 588995 bytes