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Methods: Poly A+ RNA was prepared from neonatal (2-day) and adult (42-day) cardiac myocytes and whole ventricular tissue and mRNA expression determined by reverse transcription-polymerase chain ...

Cardiovascular Research, Original Article, Caryn J McGill, Gavin Brooks

Date : 01/05/1997 Item size : 190838 bytes

[...]AT2 receptor stimulation inhibits growth and promotes apoptosis, an important mechanism during development and tissue remodeling. [...]ANG stimulates the release of nitric oxide (NO)/cGMP via ...

Cardiovascular Research, Review, Olaf Jöhren, Andreas Dendorfer, Peter Dominiak

Date : 01/06/2004 Item size : 423872 bytes

Abstract Aims Cultured fibroblasts of hypoxia-stimulated remodelled pulmonary artery (PA) adventitia proliferate at a greater rate compared with those of normal adventitia. Since protein kinase C ...

Cardiovascular Research, Original Article, Mita Das, Nana Burns, Shelly J. Wilson, Wojciech M. Zawada, Kurt R. Stenmark

Date : 01/06/2008 Item size : 314689 bytes

Abstract Fibroblast growth factor 2 (FGF-2), a multifunctional polypeptide that affects cell growth and differentiation and becomes upregulated by stress, is expressed as AUG-initiated 18 kDa FGF-2 ...

Cardiovascular Research, Review, Elissavet Kardami, Zhi-Sheng Jiang, Sarah K Jimenez, Cheryl J Hirst, Farah Sheikh, Peter Zahradka, Peter A Cattini

Date : 15/08/2004 Item size : 376385 bytes

All members of the PDZLIM Enigma family, including ENH, are cytoplasmic proteins that bind to the cytoskeleton through a direct interaction between their PDZ domain and α-actinin,1 thus localizing ...

Cardiovascular Research, Editorial, Anne-Marie Lompré

Date : 01/06/2010 Item size : 162760 bytes

Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death Abstract Objective: The signaling pathways ...

Cardiovascular Research, Original Article, Frank Jung, Judith Haendeler, Christine Goebel, Andreas M. Zeiher, Stefanie Dimmeler

Date : 01/10/2000

Prostacyclin production in rat aortic smooth muscle cells: role of protein kinase C, phospholipase D and cyclooxygenase-2 expression Abstract Objective: The present study was designed to investigate ...

Cardiovascular Research, Original Article, Miguel A Frias, Frédérique Dubouloz, Michela C Rebsamen, Ursula Lang

Date : 01/11/2003

Abstract Isolated cardiomyocytes, obtained by enzymatic digestion of whole hearts, have multiple advantages, most related to their accessibility to microscopic visualization, beyond the obvious ...

Cardiovascular Research, Review, Roberto J. Diaz, Gregory J. Wilson

Date : 01/05/2006

With great interest we have read the recently published article by Lin et al. 1 where PKCδ is described to regulate uptake of oxLDL and the resultant foam cell formation, thereby suggesting a ...

Cardiovascular Research, Letter to the Editor, Katka Szilagyi, Timo K. van den Berg

Date : 01/02/2013

KeywordsInsulinSignal transductionMyocardial metabolismDiabetesGlucose transportAbbreviationsACC = acetyl-CoA carboxylaseAMP-PK = protein serine/threonine kinase activated by 5AMPCPT-I = carnitine ...

Cardiovascular Research, Review, Roger W. Brownsey, Adrienne N. Boone, Michael F. Allard

Date : 01/04/1997