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In rings from rats with heart failure, acetylcholine-induced relaxation was attenuated (maximum relaxation, Rmax 54±3%) when compared with rings from sham-operated animals (79±3%, n=12, ...

Cardiovascular Research, Original Article, Johann Bauersachs, Ingrid Fleming, Daniela Fraccarollo, Rudi Busse, Georg Ertl

Date : 01/08/2001 Item size : 280141 bytes

Abstract Background: Men and women are differently affected by coronary artery disease, suggesting an important role of sex steroids. [...]testosterone (T) treatment is increasingly used in elderly ...

Cardiovascular Research, Original Article, Matthias Nahrendorf, Stefan Frantz, Kai Hu, Constantin von zur Mühlen, Maria Tomaszewski, Heidi Scheuermann, Ralf Kaiser, Virginija Jazbutyte, Stephanie ...

Date : 01/02/2003 Item size : 275493 bytes

Abstract Objectives: To investigate the effects of adding the selective aldosterone receptor antagonist eplerenone to ACE inhibition on endothelium-dependent vasodilation in rats with chronic heart ...

Cardiovascular Research, Original Article, Andreas Schäfer, Daniela Fraccarollo, Steven K Hildemann, Piet Tas, Georg Ertl, Johann Bauersachs

Date : 01/06/2003

Cardioprotection by long-term ETA receptor blockade and ACE inhibition in rats with congestive heart failure: mono- versus combination therapy Abstract Objectives: We investigated the effects of ...

Cardiovascular Research, Original Article, Daniela Fraccarollo, Johann Bauersachs, Markus Kellner, Paolo Galuppo, Georg Ertl

Date : 01/04/2002

Abstract Objective Standard drugs post-myocardial infarction (MI) such as angiotensin converting enzyme (ACE) and 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) ...

Cardiovascular Research, Original Article, Thomas Thum, Daniela Fraccarollo, Paolo Galuppo, Dimitrios Tsikas, Stefan Frantz, Georg Ertl, Johann Bauersachs

Date : 01/04/2006

Methods: MI was produced by coronary artery ligation in adult male Wistar rats. [...]the acute application of ACE inhibitors along with thrombolytic therapy showed some survival benefits as early as ...

Cardiovascular Research, Original Article, Kai Hu, Peter Gaudron, Hans-Joachim Anders, Frank Weidemann, Oliver Turschner, Matthias Nahrendorf, Georg Ertl

Date : 01/08/1998

Abstract Objectives: To elucidate the effect of selective endothelin ETA- and mixed ETA/B-receptor antagonists on endothelial vasomotor dysfunction in rats with heart failure after myocardial ...

Cardiovascular Research, Original Article, Johann Bauersachs, Daniela Fraccarollo, Paolo Galuppo, Julian Widder, Georg Ertl

Date : 01/07/2000

The mechanisms involved in the loss of physiological daynight variation are still unclear, but a continuously active sympathetic nervous system could play a role. The present study evaluated ...

Cardiovascular Research, Original Article, Klaus Witte, Kai Hu, Johanna Swiatek, Claudia Müssig, Georg Ertl, Björn Lemmer

Date : 01/08/2000

Vascular endothelial dysfunction and superoxide anion production in heart failure are p38 MAP kinase-dependent Abstract Objective: The mitogen-activated protein (MAP) kinase system, especially the ...

Cardiovascular Research, Original Article, Julian Widder, Thomas Behr, Daniela Fraccarollo, Kai Hu, Paolo Galuppo, Piet Tas, Christiane E Angermann, Georg Ertl, Johann Bauersachs

Date : 01/07/2004

Sustained activation of nuclear factor kappa B and activator protein 1 in chronic heart failure Abstract Objective: Innate immune response proteins such as inflammatory cytokines, inducible nitric ...

Cardiovascular Research, Original Article, Stefan Frantz, Daniela Fraccarollo, Helga Wagner, Thomas M Behr, Philip Jung, Christiane E Angermann, Georg Ertl, Johann Bauersachs

Date : 01/03/2003