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Introduction Atherosclerotic plaque rupture, occurring either spontaneously or during coronary interventions, results in the release of atheromatous and/or thrombotic material into the coronary ...

Cardiovascular Research, Original Article, Andreas Skyschally, Rainer Schulz, Petra Gres, Ina Konietzka, Claus Martin, Michael Haude, Raimund Erbel, Gerd Heusch

Date : 01/08/2004 Item size : 260310 bytes

[...]the coronary microcirculation is also a target of both injury by myocardial ischaemia/reperfusion and protection from it. The lack of translation is not the consequence of a species problem, ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Gerd Heusch, Petra Kleinbongard, Andreas Skyschally, Bodo Levkau, Rainer Schulz, Raimund Erbel

Date : 01/05/2012 Item size : 569039 bytes

Acute myocardial infarction remains a significant health problem throughout the world, and for those patients surviving the immediate event, infarct size is the main determinant of further ...

Cardiovascular Research, VIEWPOINT EDITORIAL, Gerd Heusch, Rainer Schulz

Date : 01/10/2009 Item size : 328965 bytes

Abstract Objective: Short-term myocardial hibernation is characterized by an adaptation of contractile function to the reduced blood flow, the recovery of creatine phosphate content and lactate ...

Cardiovascular Research, Original Article, Claus Martin, Rainer Schulz, Jochen Rose, Gerd Heusch

Date : 01/08/1998

The cardioprotection achieved by IPw is completely abolished by blockade of bradykinin-B2-receptors. Since activation of bradykinin-B2-receptors subsequently activates cyclooxygenase, we now tested ...

Cardiovascular Research, Original Article, Petra Gres, Rainer Schulz, Johanna Jansen, Christian Umschlag, Gerd Heusch

Date : 15/08/2002

Abstract Objectives: In human end-stage heart failure as well as in experimental animal models of heart failure, G-protein-coupled receptor kinase activity (GRK) is increased while β-adrenoceptor ...

Cardiovascular Research, Original Article, Kirsten Leineweber, Patrick Rohe, Anja Beilfuß, Christina Wolf, Heike Sporkmann, Heike Bruck, Heinz-Günther Jakob, Gerd Heusch, Thomas Philipp, ...

Date : 01/06/2005

Methods and results Anaesthetized pigs were subjected to 90 min left anterior descending coronary artery hypoperfusion and 120 min reperfusion. The activation of reperfusion injury salvage kinases ...

Cardiovascular Research, Original Article, Judith Musiolik, Patrick van Caster, Andreas Skyschally, Kerstin Boengler, Petra Gres, Rainer Schulz, Gerd Heusch

Date : 01/01/2010

Methods: In enflurane-anaesthetised swine the coronary blood flow through the left anterior descending coronary artery was decreased to reduce regional contractile function (microsonometry) by ...

Cardiovascular Research, Original Article, Hartmut Lüss, Peter Boknıék, Gerd Heusch, Frank Ulrich Müller, Joachim Neumann, Wilhelm Schmitz, Rainer Schulz

Date : 01/03/1998

The pivotal importance of myocardial perfusion for the maintenance of myocardial contractile function was already recognized some 60 years ago [1], but the functional and metabolic consequences of ...

Cardiovascular Research, Review, Dirk J Duncker, Rainer Schulz, Roberto Ferrari, David Garcia-Dorado, Carlo Guarnieri, Gerd Heusch, Pieter D Verdouw

Date : 01/06/1998

In the context of coronary artery disease, myocardial hibernation was originally seen as a chronic, adaptive reduction of myocardial contractile function in response to a reduction of myocardial ...

Cardiovascular Research, Review, Gerd Heusch, Roberto Ferrari, David J Hearse, Tom J.C Ruigrok, Rainer Schulz

Date : 01/12/1997