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Ehjcardiovascrec

Abstract Objective: The purpose of this study was to compare protective effects of AMP579 and adenosine (Ado) at reperfusion (R) on inhibition of polymorphonuclear neutrophil (PMN) activation, ...

Cardiovascular Research, Original Article, Jason M Budde, Daniel A Velez, Zhi-Qing Zhao, Kenneth L Clark, Cullen D Morris, Satoshi Muraki, Robert A Guyton, Jakob Vinten-Johansen

Date : 01/08/2000 Item size : 321171 bytes
Ehjcardiovascrec

Preconditioning, a series of transient intervals of ischaemia and reperfusion applied before the lethal index ischaemic event, sets in motion molecular and cellular mechanisms that increase ...

Cardiovascular Research, Review, Asger Granfeldt, David J. Lefer, Jakob Vinten-Johansen

Date : 15/07/2009 Item size : 648421 bytes
Ehjcardiovascrec

The backdrop: cardioprotection lost in translation Early work from Dr Braunwald's group demonstrated that the infarct size was not a predetermined entity, but could be modified by interventions ...

Cardiovascular Research, EDITORIALS: SPOTLIGHT ON LANDMARK PAPERS IN, Jakob Vinten-Johansen

Date : 01/11/2012 Item size : 210501 bytes
Ehjcardiovascrec

Reperfusion injury is expressed as endothelial and microvascular dysfunction, impaired blood flow, metabolic dysfunction, cellular necrosis, and apoptosis. Postconditioning may also inhibit ...

Cardiovascular Research, Review, Zhi-Qing Zhao, Jakob Vinten-Johansen

Date : 01/05/2006 Item size : 477372 bytes
Ehjcardiovascrec

Control (n=8): no intervention at R; Ischemic preconditioning (IPC) (n=8): the LCA was occluded for 5 min followed by 10 min of R before the index occlusion; Post-con 1 (n=8): after LCA occlusion, ...

Cardiovascular Research, Original Article, Hajime Kin, Zhi-Qing Zhao, He-Ying Sun, Ning-Ping Wang, Joel S. Corvera, Michael E. Halkos, Faraz Kerendi, Robert A. Guyton, Jakob Vinten-Johansen

Date : 01/04/2004
Ehjcardiovascrec

ATP depletion, cell swelling or cell rupture, loss of cell membrane integrity and a significant inflammatory response characterize the morphologic manifestation of necrosis [1,2]. [14] reported that ...

Cardiovascular Research, Original Article, Masanori Nakamura, Ning-Ping Wang, Zhi-Qing Zhao, Josiah N Wilcox, Vinod Thourani, Robert A Guyton, Jakob Vinten-Johansen

Date : 01/02/2000
Ehjcardiovascrec

PI group), and DNA ladder occurred in all experimental animals, suggesting that myocardial apoptosis is primarily elicited by R. Densitometrically, Western blot analysis showed significant reduction ...

Cardiovascular Research, Original Article, Zhi-Qing Zhao, Masanori Nakamura, Ning-Ping Wang, Josiah N. Wilcox, Steven Shearer, Russell S. Ronson, Robert A. Guyton, Jakob Vinten-Johansen

Date : 01/02/2000
Ehjcardiovascrec

Results Infarct size, expressed as area of necrosis as a percentage of the area at risk, AN/AAR (%), was significantly reduced by postcon compared to control (untreated) rats (39±2% vs. 53±1% ...

Cardiovascular Research, Original Article, Amanda J. Zatta, Hajime Kin, George Lee, Ningping Wang, Rong Jiang, Robert Lust, James G. Reeves, James Mykytenko, Robert A. Guyton, Zhi-Qing Zhao, Jakob ...

Date : 01/05/2006