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Methods Anterior MI was created in male heterozygous p53-deficient (p53+/ n=28) mice and sibling wild-type (p53+/+; n=29) mice by ligating the left coronary artery. Notably, p53+/ mice had a ...

Cardiovascular Research, Original Article, Hidenori Matsusaka, Tomomi Ide, Shouji Matsushima, Masaki Ikeuchi, Toru Kubota, Kenji Sunagawa, Shintaro Kinugawa, Hiroyuki Tsutsui

Date : 01/06/2006 Item size : 265690 bytes

Abstract Objectives: To assess the phosphorylation of myocardial phospholamban (PLB) and quantify protein levels of PLB and sarco/endoplasmic reticulum Ca2+ ATPase type 2 (SERCA 2) in a rabbit model ...

Cardiovascular Research, Original Article, Susan Currie, Godfrey L. Smith

Date : 01/01/1999 Item size : 286941 bytes

Congestive heart failure induces downregulation of P2X1-receptors in resistance arteries Abstract Objective: Congestive heart failure (CHF) is accompanied by enhanced peripheral sympathetic nerve ...

Cardiovascular Research, Original Article, Malin Malmsjö, Anders Bergdahl, Sebastian Möller, Xiao-He Zhao, Xiang-Ying Sun, Thomas Hedner, Lars Edvinsson, David Erlinge

Date : 01/07/1999 Item size : 267033 bytes

Abstract Aims Previously, we showed an enhanced excitatory (N-methyl d-aspartate receptor-NR1) and decreased inhibitory neuronal nitric oxide (NO) synthase (nNOS) influence within the paraventricular ...

Cardiovascular Research, Original Article, Neeru M. Sharma, Hong Zheng, Parmender P. Mehta, Yi-Fan Li, Kaushik P. Patel

Date : 01/11/2011 Item size : 307597 bytes

Despite considerable progress in the understanding and management of heart failure, its incidence, prevalence and economic burden are steadily increasing. [...]efficient preventive and therapeutic ...

Cardiovascular Research, Review, Rainer Klocke, Wen Tian, Michael T. Kuhlmann, Sigrid Nikol

Date : 01/04/2007 Item size : 378011 bytes

Methods: Post-myocardial infarct (MI)-remodeled hearts after permanent coronary artery ligation and one kidney one clip (1K1C) hypertensive hearts of male Wistar rats were exposed to 40 min of ...

Cardiovascular Research, Original Article, Min Zhu, Jianhua Feng, Eliana Lucchinetti, Gregor Fischer, Lin Xu, Thierry Pedrazzini, Marcus C. Schaub, Michael Zaugg

Date : 01/10/2006 Item size : 259568 bytes

Abstract Objective: To assess the long-term efficacy of vasopressin (AVP) V1a and V2 receptor blockade with conivaptan, alone and in combination with angiotensin converting enzyme (ACE) inhibition on ...

Cardiovascular Research, Original Article, Mareo Naitoh, John Risvanis, Leanne C. Balding, Colin I. Johnston, Louise M. Burrell

Date : 01/04/2002 Item size : 257113 bytes

Long-term treatment with neutral endopeptidase inhibitor improves cardiac function and reduces natriuretic peptides in rats with chronic heart failure Abstract Objective: Increased secretion of ...

Cardiovascular Research, Original Article, Toshiyuki Maki, Yoshihisa Nasa, Fuminari Yamaguchi, Hiroyuki Yoshida, Masaya Mori, Taku Takada, Eriko Horikawa, Kaori Okano, Satoshi Takeo

Date : 15/08/2001 Item size : 284680 bytes

Abstract Objectives: We studied the effects of chronic left coronary artery ligation on cardiac structure and function in the mouse. Methods: Morphometric studies of the left ventricle were ...

Cardiovascular Research, Original Article, Esther Lutgens, Mat J.A.P Daemen, Ebo D de Muinck, Jacques Debets, Peter Leenders, Jos F.M Smits

Date : 01/03/1999 Item size : 224883 bytes

Thirteen Wistar rats that had undergone skeletal muscle cell transplantation (n = 6) or injection of control culture medium (n = 7) in isoforms areas after myocardial infarction created by coronary ...

Cardiovascular Research, Original Article, Nawwar Al Attar, Claire Carrion, Said Ghostine, Isabelle Garcin, Jean-Thomas Vilquin, Albert A. Hagège, Philippe Menasché

Date : 01/04/2003 Item size : 197946 bytes