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Abstract Objectives: IKr blockade is ineffective in preventing ventricular fibrillation elicited by the interaction between acute myocardial ischemia and elevated sympathetic ...

Cardiovascular Research, Original Article, Philip B. Adamson, Emilio Vanoli, Stephen S. Hull, Robert D. Foreman, Peter J. Schwartz

Date : 01/10/1998 Item size : 244125 bytes

Abstract Objective: We tested the hypothesis that the rate of adaptation of coronary metabolic vasodilatation and autoregulation is modulated by the cardiac nerves. Reflex coronary vasodilatation ...

Cardiovascular Research, Original Article, Isabelle Vergroesen, Daphne Merkus, Jurgen W.G.E van Teeffelen, Jenny Dankelman, Jos A.E Spaan, Harry B van Wezel, Mark I.M Noble, Angela J Drake-Holland

Date : 01/12/1999 Item size : 244066 bytes

Methods: MI was induced by permanent ligation of the left coronary artery in male normotensive Wistar rats. At these time points, mean arterial blood pressure (MAP), heart rate (HR), left ...

Cardiovascular Research, Original Article, Steffen Sandmann, Jiang-Yong Min, Achim Meissner, Thomas Unger

Date : 01/10/1999 Item size : 409874 bytes

Abstract Objective: Because statins promote endogenous nitric oxide (NO) production in vessels by increasing endothelial nitric oxide synthase (eNOS), we evaluated the clinical benefit and efficiency ...

Cardiovascular Research, Original Article, Jean-Noel Trochu, Seema Mital, Xiao-ping Zhang, Xiaobin Xu, Manuel Ochoa, James K Liao, Fabio A Recchia, Thomas H Hintze

Date : 01/11/2003 Item size : 293750 bytes

Abstract Objective: The aim of this study was to determine whether selective activation of the adenosine A3 receptor reduces infarct size in a Langendorff model of myocardial ischemia-reperfusion ...

Cardiovascular Research, Original Article, W.Ross Tracey, William Magee, Hiroko Masamune, Scott P Kennedy, Delvin R Knight, R.Allan Buchholz, Roger J Hill

Date : 01/02/1997 Item size : 168830 bytes

Abstract Objective: Clinical trials in patients with stable angina show that drugs that partially inhibit myocardial fatty acid oxidation reduce the symptoms of demand-induced ischemia, presumably by ...

Cardiovascular Research, Original Article, Margaret P. Chandler, Pedro N. Chavez, Tracy A. McElfresh, Hazel Huang, Charles S. Harmon, William C. Stanley

Date : 01/07/2003 Item size : 282851 bytes

Conclusions: In the ischemic region, intraneuronal DHPG production was affected by alterations in monoamine oxidase activity, NE mobilization from stored vesicles, and carrier-mediated NE ...

Cardiovascular Research, Original Article, Tsuyoshi Akiyama, Toji Yamazaki

Date : 01/01/2001 Item size : 223499 bytes

Methods: Rats, treated with 25 mg/kg aspirin daily from 2 days before to 3 weeks after coronary artery ligation, were chronically instrumented with an electromagnetic flow-probe and arterial and ...

Cardiovascular Research, Original Article, Regien G Schoemaker, Pramod R Saxena, Ed A.J Kalkman

Date : 01/01/1998 Item size : 230087 bytes

Abstract Objective: To test the hypothesis that mild hypothermia potentiates the cardioprotection afforded by ischaemic preconditioning so that infarct size limitation can be obtained after coronary ...

Cardiovascular Research, Original Article, Mirella A van den Doel, Ben C.G Gho, Stanley Y Duval, Regien G Schoemaker, Dirk J Duncker, Pieter D Verdouw

Date : 01/01/1998 Item size : 204853 bytes

Abstract Objective Many patients with heart failure have whole-body insulin resistance and reduced cardiac fluorodeoxyglucose uptake, but whether these metabolic changes have detrimental effects on ...

Cardiovascular Research, Original Article, Andrew J. Murray, Craig A. Lygate, Mark A. Cole, Carolyn A. Carr, George K. Radda, Stefan Neubauer, Kieran Clarke

Date : 01/07/2006 Item size : 331475 bytes