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[...]the coronary microcirculation is also a target of both injury by myocardial ischaemia/reperfusion and protection from it. The lack of translation is not the consequence of a species problem, ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Gerd Heusch, Petra Kleinbongard, Andreas Skyschally, Bodo Levkau, Rainer Schulz, Raimund Erbel

Date : 01/05/2012 Item size : 569039 bytes

[...]window of preconditioning normalizes palmitate use for oxidation and improves function during low-flow ischaemia Conclusion Thus, the second window of preconditioning normalized oxidative ...

Cardiovascular Research, Original Article, Raymond K. Kudej, Mathew Fasano, Xin Zhao, Gary D. Lopaschuk, Susan K. Fischer, Dorothy E. Vatner, Stephen F. Vatner, E. Douglas Lewandowski

Date : 01/12/2011 Item size : 326863 bytes

Introduction New treatment strategies are required to reduce myocardial injury and improve clinical outcomes in patients with coronary heart disease, the leading cause of death worldwide. Following ...

Cardiovascular Research, Review, Derek J. Hausenloy, Derek M. Yellon

Date : 01/08/2008 Item size : 380542 bytes

In that first study it was reported that several hours were required for complete recovery of regional contractility following a 5 min occlusion of the left anterior descending coronary artery in ...

Cardiovascular Research, Editorial, Jos M.J. Lamers

Date : 01/06/1999 Item size : 236854 bytes

Abstract Objective: To test the hypothesis that mild hypothermia potentiates the cardioprotection afforded by ischaemic preconditioning so that infarct size limitation can be obtained after coronary ...

Cardiovascular Research, Original Article, Mirella A van den Doel, Ben C.G Gho, Stanley Y Duval, Regien G Schoemaker, Dirk J Duncker, Pieter D Verdouw

Date : 01/01/1998 Item size : 204853 bytes

Acute myocardial infarction remains a significant health problem throughout the world, and for those patients surviving the immediate event, infarct size is the main determinant of further ...

Cardiovascular Research, VIEWPOINT EDITORIAL, Gerd Heusch, Rainer Schulz

Date : 01/10/2009 Item size : 328965 bytes

Abstract Objective: The inducible isoform of nitric oxide synthase (iNOS) is known to be a trigger of the heat stress (HS)-induced cardioprotection. Since iNOS also appears to mediate various forms ...

Cardiovascular Research, Original Article, Claire Arnaud, Diane Godin-Ribuot, Serge Bottari, André Peinnequin, Marie Joyeux, Pierre Demenge, Christophe Ribuot

Date : 01/04/2003 Item size : 295317 bytes

The backdrop: cardioprotection lost in translation Early work from Dr Braunwald's group demonstrated that the infarct size was not a predetermined entity, but could be modified by interventions ...

Cardiovascular Research, EDITORIALS: SPOTLIGHT ON LANDMARK PAPERS IN, Jakob Vinten-Johansen

Date : 01/11/2012 Item size : 210501 bytes

Reperfusion injury is expressed as endothelial and microvascular dysfunction, impaired blood flow, metabolic dysfunction, cellular necrosis, and apoptosis. Postconditioning may also inhibit ...

Cardiovascular Research, Review, Zhi-Qing Zhao, Jakob Vinten-Johansen

Date : 01/05/2006 Item size : 477372 bytes

PrPSc is the major constituent of prions, the aetiological agents of a group of rare and incurable neurodegenerative disorders, named transmissible spongiform encephalopathies (TSEs) or prion ...

Cardiovascular Research, Original Article, Filippo Zanetti, Andrea Carpi, Roberta Menabò, Marco Giorgio, Rainer Schulz, Guro Valen, Anton Baysa, Maria Lina Massimino, Maria Catia Sorgato, ...

Date : 01/10/2014