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Consistent with a role in promoting necroptosis, adenoviral overexpression of RIP3 in neonatal rat cardiomyocytes and stimulation with TNF-α induced the formation of a complex of RIP1 and ...

Cardiovascular Research, Cardiac biology and remodelling, Mark Luedde, Matthias Lutz, Natalie Carter, Justyna Sosna, Christoph Jacoby, Mihael Vucur, Jérémie Gautheron, Christoph Roderburg, ...

Date : 15/07/2014 Item size : 330213 bytes

Methods Anterior MI was created in male heterozygous p53-deficient (p53+/ n=28) mice and sibling wild-type (p53+/+; n=29) mice by ligating the left coronary artery. Notably, p53+/ mice had a ...

Cardiovascular Research, Original Article, Hidenori Matsusaka, Tomomi Ide, Shouji Matsushima, Masaki Ikeuchi, Toru Kubota, Kenji Sunagawa, Shintaro Kinugawa, Hiroyuki Tsutsui

Date : 01/06/2006 Item size : 265690 bytes

Basal left ventricular end-diastolic pressure (in mmHg) was reduced in the groups in which cariporide was started 1 week pre (16.0±1.7) or 30 min (12.5±1.1), 3 h (11.8±1.0) and 24 h ...

Cardiovascular Research, Original Article, Heidi Spitznagel, Oliver Chung, Qin-Gui Xia, Birthe Rossius, Sascha Illner, Gunnar Jähnichen, Steffen Sandmann, Alexander Reinecke, Mat J.A.P. Daemen, ...

Date : 01/04/2000 Item size : 271349 bytes

Abstract Objectives: IKr blockade is ineffective in preventing ventricular fibrillation elicited by the interaction between acute myocardial ischemia and elevated sympathetic ...

Cardiovascular Research, Original Article, Philip B. Adamson, Emilio Vanoli, Stephen S. Hull, Robert D. Foreman, Peter J. Schwartz

Date : 01/10/1998 Item size : 244125 bytes

Abstract Aims Our aim was to test the hypothesis that angiotensin II receptor blockade combined with exercise training after myocardial infarction (MI) could attenuate post-MI left ventricular ...

Cardiovascular Research, Original Article, Xiaohua Xu, Wenhan Wan, Lisa Ji, Shunhua Lao, Anthony S. Powers, Weiyan Zhao, John M. Erikson, John Q. Zhang

Date : 01/06/2008 Item size : 367993 bytes

Abstract Background: Traffic of potentially harmful cytosolic messengers through gap junctions might cause increased injury during ischemia. The present study was to determine whether the infarct ...

Cardiovascular Research, Original Article, Tsung-Ming Lee, Mei-Shu Lin, Tsai-Fwu Chou, Chang-Her Tsai, Nen-Chung Chang

Date : 01/07/2004 Item size : 280862 bytes

[...]passive smoking has been also shown to represent an important risk factor for coronary artery disease. [...]the incidence of coronary artery and cerebrovascular diseases in ex-smokers ...

Cardiovascular Research, Review, Chiara Bolego, Andrea Poli, Rodolfo Paoletti

Date : 15/02/2002 Item size : 414871 bytes

Abstract Objective: Although it is generally accepted that endurance training improves cardiac function after myocardial infarction the sub-cellular mechanisms are uncertain. The present study ...

Cardiovascular Research, Original Article, Ulrik Wisløff, Jan P. Loennechen, Susan Currie, Godfrey L. Smith, Øyvind Ellingsen

Date : 01/04/2002 Item size : 371926 bytes

Methods: Chronic MI was induced in young adult (3.5 months) and aged (18 months) female SpragueDawley rats by ligation of the left coronary artery. Results: Aged control rats differed from young ...

Cardiovascular Research, Original Article, Alexander Deten, Grit Marx, Wilfried Briest, Hans Christian Volz, Heinz-Gerd Zimmer

Date : 01/05/2005 Item size : 291031 bytes

Abstract Ischemic preconditioning is a well-established phenomenon first described in experimental preparations in which brief episodes of ischemia/reperfusion applied prior to a longer coronary ...

Cardiovascular Research, Review, Robert A. Kloner, Shereif H. Rezkalla

Date : 01/05/2006 Item size : 474439 bytes