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Occlusion of the left main coronary artery (one hour) followed by reperfusion (one hour) in the anesthetized rat caused severe cardiac necrosis, neutrophil infiltration, and increased plasma creatine ...

Cardiovascular Research, Original Article, Basilia Zingarelli, Salvatore Cuzzocrea, Zsuzsanna Zsengellér, Andrew L. Salzman, Csaba Szabó

Date : 01/11/1997 Item size : 197233 bytes

The demonstration that gene therapy can improve collateral function presents one of the solutions to the conundrum, since gene therapy can be considered a sophisticated form of a sustained delivery ...

Cardiovascular Research, Review, Stephen E. Epstein, Shmuel Fuchs, Yi Fu Zhou, Richard Baffour, Ran Kornowski

Date : 16/02/2001 Item size : 488164 bytes

Abstract Objectives: IKr blockade is ineffective in preventing ventricular fibrillation elicited by the interaction between acute myocardial ischemia and elevated sympathetic ...

Cardiovascular Research, Original Article, Philip B. Adamson, Emilio Vanoli, Stephen S. Hull, Robert D. Foreman, Peter J. Schwartz

Date : 01/10/1998 Item size : 244125 bytes

Abstract Objective: We tested the hypothesis that occlusion of the superior mesenteric artery induces late preconditioning against myocardial infarction and examined the effects of pharmacological ...

Cardiovascular Research, Original Article, You-Ping Wang, Hui Xu, Kazuhiro Mizoguchi, Masahiro Oe, Hajime Maeta

Date : 01/02/2001 Item size : 266841 bytes

In this article it was shown that the ST-segment elevation occurring early after occlusion of the left descending coronary artery was closely related to the depletion of the necrotic cells from ...

Cardiovascular Research, Update review, Andrè G Kléber

Date : 01/01/2000 Item size : 279121 bytes

Novel molecular approaches have helped to improve our understanding of the process of collateral vessel formation in recent years. Besides the process of true angiogenesis, i.e. the formation of new ...

Cardiovascular Research, Review, Johannes Waltenberger

Date : 16/02/2001 Item size : 254383 bytes

Despite several recent successful advances in the therapy of acute coronary syndromes based on limiting the extent of myocardial damage that ensues following occlusion of a major coronary artery by ...

Cardiovascular Research, Review, Neil C Chi, Joel S Karliner

Date : 15/02/2004 Item size : 504888 bytes

Angiogenic gene therapy for heart disease: a review of animal studies and clinical trials Abstract The current published clinical literature on angiogenic gene therapy for the treatment of ...

Cardiovascular Research, Review, H.Kirk Hammond, M.Dan McKirnan

Date : 16/02/2001 Item size : 206864 bytes

Conclusions: In the ischemic region, intraneuronal DHPG production was affected by alterations in monoamine oxidase activity, NE mobilization from stored vesicles, and carrier-mediated NE ...

Cardiovascular Research, Original Article, Tsuyoshi Akiyama, Toji Yamazaki

Date : 01/01/2001 Item size : 223499 bytes

Results: In vivo ischemia/reperfusion caused significant coronary vascular endothelial dysfunction as evidenced by reduced endothelium-dependent vasorelaxation, decreased nitric oxide (NO) ...

Cardiovascular Research, Original Article, Heng Ma, Hai-Feng Zhang, Lu Yu, Quan-Jiang Zhang, Jia Li, Jian-Hua Huo, Xue Li, Wen-Yi Guo, Hai-Chang Wang, Feng Gao

Date : 01/01/2006 Item size : 228321 bytes