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Abstract Objectives: To assess the phosphorylation of myocardial phospholamban (PLB) and quantify protein levels of PLB and sarco/endoplasmic reticulum Ca2+ ATPase type 2 (SERCA 2) in a rabbit model ...

Cardiovascular Research, Original Article, Susan Currie, Godfrey L. Smith

Date : 01/01/1999 Item size : 286941 bytes

Pharmacological adenosine receptor blockade during preconditioning abolishes the acquisition of delayed protection, while transient adenosine A1 or A3 receptor activation fully recapitulates ...

Cardiovascular Research, Review, G.F Baxter

Date : 15/08/2002 Item size : 442878 bytes

Methods: Post-myocardial infarct (MI)-remodeled hearts after permanent coronary artery ligation and one kidney one clip (1K1C) hypertensive hearts of male Wistar rats were exposed to 40 min of ...

Cardiovascular Research, Original Article, Min Zhu, Jianhua Feng, Eliana Lucchinetti, Gregor Fischer, Lin Xu, Thierry Pedrazzini, Marcus C. Schaub, Michael Zaugg

Date : 01/10/2006 Item size : 259568 bytes

Abstract Objective: Infarct size (IS) reduction by ischemic preconditioning (IPC) has been assessed in the heart in which coronary stenosis (CS)-induced chronic ischemia was not present. Protein ...

Cardiovascular Research, Original Article, Kenichi Watanabe, Hiroyuki Yaoita, Kazuei Ogawa, Masayoshi Oikawa, Kazuhira Maehara, Yukio Maruyama

Date : 01/08/2006 Item size : 258404 bytes

Tumor necrosis factor-α enhances hypoxia–reoxygenation-mediated apoptosis in cultured human coronary artery endothelial cells: critical role of protein kinase C Abstract Background: Ischemia ...

Cardiovascular Research, Original Article, Dayuan Li, Baichun Yang, Jawahar L. Mehta

Date : 01/06/1999 Item size : 271330 bytes

The primary manifestations of myocardial I/R injury are myocyte death, arrhythmias, and contractile dysfunction.35 Patients surviving AMI are susceptible to recurrent angina, reinfarction, ...

Cardiovascular Research, Review, M.A. Hassan Talukder, Jay L. Zweier, Muthu Periasamy

Date : 01/12/2009 Item size : 482430 bytes

Methods: Cyclosporine A, a potent protein 2B or calcium/calmodulin-dependent phosphatase (PP) inhibitor, was administered to isolated rabbit hearts starting either 15 min prior to or 10 or 20 min ...

Cardiovascular Research, Original Article, Christof Weinbrenner, Guang S Liu, James M Downey, Michael V Cohen

Date : 01/06/1998

Methods In situ rabbit hearts underwent 30min of regional ischemia and 3h of reperfusion, and postconditioning was effected with four cycles of 30-s reperfusion/30-s coronary artery occlusion at the ...

Cardiovascular Research, Original Article, Sebastian Philipp, Xi-Ming Yang, Lin Cui, Amanda M. Davis, James M. Downey, Michael V. Cohen

Date : 01/05/2006

[11] (pages 130135) in this issue. 1 Introduction A widely accepted risk factor for the development of coronary artery disease is an elevated level of plasma cholesterol. Synthetic derivatives of ...

Cardiovascular Research, Editorial, Steven J Miller

Date : 01/10/2001

Results: Compared with rabbits fed with a normal diet, HC rabbits had increased caspase-3 activity, apoptotic cell death and retarded contractile function recovery after reperfusion. Treatment with ...

Cardiovascular Research, Original Article, Hui-Rong Liu, Ling Tao, Erhe Gao, Bernard L Lopez, Theodore A Christopher, Robert N Willette, Eliot H Ohlstein, Tian-Li Yue, Xin-Liang Ma

Date : 01/04/2004