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Methods and results Using miRNA microarray, real-time PCR, and luciferase reporter assay, our study showed that miR-490-3p and insulin-like growth factor-1 (IGF1) expression were down-regulated, ...

Cardiovascular Research, Vascular biology, Yufa Sun, Deyou Chen, Lijuan Cao, Rongrong Zhang, Jie Zhou, Haiyan Chen, Yinyin Li, Minglong Li, Jian Cao, Zhe Wang

Date : 01/11/2013 Item size : 279466 bytes

Introduction Systemic hypertension, hypercholesterolaemia, and diabetes are associated with endothelial dysfunction that promotes inflammation, oxidation of lipoproteins, smooth muscle proliferation, ...

Cardiovascular Research, Review, Kwang Kon Koh, Pyung Chun Oh, Michael J. Quon

Date : 01/03/2009 Item size : 535454 bytes

Abstract Aims Vascular calcification (VC) is a significant contributor to cardiovascular mortality in patients with chronic kidney disease (CKD) and coronary artery disease (CAD). Methods and ...

Cardiovascular Research, Original Article, Tzong-Shi Lu, Kenneth Lim, Guerman Molostvov, Yun-Chun Yang, Szu-Yu Yiao, Daniel Zehnder, Li-Li Hsiao

Date : 01/12/2012 Item size : 302217 bytes

Up-regulation of TGF-β1 after arterial injury results in the activation of various downstream pathways which stimulate the proliferation and migration of vascular smooth muscle cells, as well as ...

Cardiovascular Research, Review, Razi Khan, Alex Agrotis, Alex Bobik

Date : 01/05/2007 Item size : 539717 bytes

Methods: Twenty-six PHPT patients (mean±SD; age 55±15y, serum calcium 3.00±0.37 mmol/l, serum phosphate 0.79±0.21 mmol/l, iPTH 249±262 pg/ml) with no evidence of coronary artery ...

Cardiovascular Research, Original Article, Thomas Neunteufl, Reinhold Katzenschlager, Claudette Abela, Karam Kostner, Bruno Niederle, Franz Weidinger, Thomas Stefenelli

Date : 01/11/1998 Item size : 251478 bytes

[...]the relationship between inflammation with atherosclerosis and myocardial ischemia is now an area of active investigation. Other studies [14] have shown that inhibition of release of ...

Cardiovascular Research, Review, J.L Mehta, D.Y Li

Date : 01/08/1999

Introduction Endothelin-1 (ET-1) plays an important role in various cardiovascular diseases such as coronary artery disease (CAD), pulmonary hypertension (PH), and high-altitude disease14 through its ...

Cardiovascular Research, ORIGINAL ARTICLES: SPOTLIGHT ON SMOOTH MUSCLE CELLS AND VASCULAR DISEASES, Tetsuya Hisada, Makoto Ayaori, Nobuhiro Ohrui, Hiroshi Nakashima, Kazuhiro Nakaya, Harumi ...

Date : 15/07/2012

KeywordsCoronary angioplastyEndothelinRestenosisSmooth muscle cell proliferationExtracellular matrixTime for primary review 31 days 1 Introduction Percutaneous transluminal angioplasty (PTCA) was ...

Cardiovascular Research, Review, Michael Kirchengast, Klaus Münter

Date : 01/09/1998

Abstract Objective: To examine the hypothesis that insulin and insulin-like growth factor I (IGF-I) attenuate endothelin-induced contraction of porcine coronary epicardial arteries in vitro. Both ...

Cardiovascular Research, Original Article, David Hasdai, David R. Holmes, Darcy M. Richardson, Uzzi Izhar, Amir Lerman

Date : 01/09/1998

The angiopoietin–tie2 system in coronary artery endothelium prevents oxidized low-density lipoprotein-induced apoptosis Abstract Objectives: A healthy, intact coronary artery endothelium is ...

Cardiovascular Research, Original Article, Injune Kim, Sang-Ok Moon, Chang-Yeop Han, Youngmi Kim Pak, Sung Ki Moon, Jong Jun Kim, Gou Young Koh

Date : 01/03/2001