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Methods and results Rat isolated hearts were subjected to reversible left coronary artery occlusion (ischaemia-reperfusion) and infarct size was assessed by the tetrazolium staining ...

Cardiovascular Research, Cardiac biology and remodelling, Justin S. Bice, Yvonne Keim, Johannes-Peter Stasch, Gary F. Baxter

Date : 01/02/2014 Item size : 282285 bytes

Methods: Chronic MI was induced in young adult (3.5 months) and aged (18 months) female SpragueDawley rats by ligation of the left coronary artery. Results: Aged control rats differed from young ...

Cardiovascular Research, Original Article, Alexander Deten, Grit Marx, Wilfried Briest, Hans Christian Volz, Heinz-Gerd Zimmer

Date : 01/05/2005 Item size : 291031 bytes

Abstract Objectives: Pulmonary hypertension (PH) and lung structural remodeling are frequent complications of congestive heart failure (CHF). Here, we investigate the natural behavior of the ...

Cardiovascular Research, Original Article, Jean-François Jasmin, Isabelle Mercier, Robert Hnasko, Michelle W.-C Cheung, Herbert B Tanowitz, Jocelyn Dupuis, Michael P Lisanti

Date : 01/09/2004 Item size : 281180 bytes

Abstract Objective: Myocardial protection can be achieved by brief ischemia-reperfusion of remote organs, a phenomenon described as remote preconditioning (RPC). Since the intracellular mechanisms ...

Cardiovascular Research, Original Article, Sebastian Wolfrum, Kathrin Schneider, Marc Heidbreder, Julie Nienstedt, Peter Dominiak, Andreas Dendorfer

Date : 15/08/2002 Item size : 247074 bytes

Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat Methods: The descending left coronary artery of male rats (Rattus ...

Cardiovascular Research, Original Article, J.Thomas Peterson, Hua Li, Lisa Dillon, John W. Bryant

Date : 01/05/2000

Abstract Objective: The mechanism by which ischemic preconditioning protects the heart is presumed to be related to the reduction of energy consumption during a subsequent myocardial ...

Cardiovascular Research, Original Article, Yasushi Takasaki, Naoto Adachi, Kentaro Dote, Shinzo Tsubota, Toshihiro Yorozuya, Tatsuru Arai

Date : 01/08/1998

Abstract Aims Blockade of mineralocorticoid receptors in the central nervous system (CNS) prevents sympathetic hyperactivity and improves left ventricle (LV) function in rats post-myocardial ...

Cardiovascular Research, Original Article, Bing S. Huang, Roselyn A. White, Monir Ahmad, Junhui Tan, Arco Y. Jeng, Frans H.H. Leenen

Date : 15/02/2009

Methods and results EMP were generated from human coronary endothelial cells (HCAEC) exposed to high glucose concentrations in order to mimic diabetic conditions. Immunofluorescent experiments ...

Cardiovascular Research, Original Article, Felix Jansen, Xiaoyan Yang, Bernardo S. Franklin, Marion Hoelscher, Theresa Schmitz, Jörg Bedorf, Georg Nickenig, Nikos Werner

Date : 01/04/2013

[...]we observed significantly increased cleavage of N-cadherin, MMP-7 activity, and apoptosis in human atherosclerotic plaques compared with control arteries, and a significant reduction in ...

Cardiovascular Research, Original Article, Helen Williams, Jason L. Johnson, Christopher L. Jackson, Stephen J. White, Sarah J. George

Date : 01/07/2010

Abstract Objective: To investigate the role of Rho A and Rho-kinase in acute myocardial ischemia/reperfusion injury and the protective effect of Rho-kinase inhibitor, Y-27632 ...

Cardiovascular Research, Original Article, Weike Bao, Erding Hu, Ling Tao, Rogely Boyce, Rosanna Mirabile, Douglas T Thudium, Xin-ling Ma, Robert N Willette, Tian-li Yue

Date : 15/02/2004