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Introduction Metabolic syndrome with visceral fat accumulation is a major risk factor for atherosclerotic cardiovascular disease.1 Adipose tissue produces a number of adipocytokines, such as leptin ...

Cardiovascular Research, Original Article, Kaho Watanabe, Rena Watanabe, Hanae Konii, Remina Shirai, Kengo Sato, Taka-aki Matsuyama, Hatsue Ishibashi-Ueda, Shinji Koba, Youichi Kobayashi, Tsutomu ...

Date : 01/05/2016 Item size : 368317 bytes

[...]research in avian models69 partially argued against this model, demonstrating that: (i) prospective CA endothelial cells do not bud from the aortic root, but instead grow into the aortic wall ...

Cardiovascular Research, Review, José María Pérez-Pomares, José Luis de la Pompa, Diego Franco, Deborah Henderson, Siew Yen Ho, Lucile Houyel, Robert G. Kelly, David Sedmera, Mary ...

Date : 01/02/2016 Item size : 479037 bytes

Migration of monocytes into tissue Monocytes play a pivotal role in tissue homeostasis, protective immunity, and both promotion and resolution of inflammation.1,2 They and their offspring, ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, Teresa Gerhardt, Klaus Ley

Date : 01/08/2015 Item size : 622859 bytes

Abstract Leucocyte transendothelial migration (TEM) involves a co-operative series of interactions between surface molecules on the leucocyte and cognate counter-ligands on the endothelial ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, William A. Muller

Date : 01/08/2015 Item size : 600823 bytes

The medial VSMC is the organizer of the inwardly directed angiogenic response arising from the adventitia by overexpressing vascular endothelial growth factor in response to lipid-stimulated ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON SMOOTH MUSCLE CELLS AND VASCULAR DISEASES, Patrick Lacolley, Véronique Regnault, Antonino Nicoletti, Zhenlin Li, Jean-Baptiste Michel

Date : 15/07/2012 Item size : 569256 bytes

Abstract Objective: The purpose of this study was to assess whether the plasma levels of soluble adhesion molecules including E-selectin, intercellular adhesion molecule-1 (ICAM-1) and vascular cell ...

Cardiovascular Research, Original Article, Kunihisa Miwa, Akihiko Igawa, Hiroshi Inoue

Date : 01/10/1997 Item size : 192206 bytes

Studies in small and large animal ischaemic heart disease models have reported that myocardial overexpression of VEGF following naked DNA transfection, Ad vectors, or AAV transduction induce ...

Cardiovascular Research, Review, Melvin Y. Rincon, Thierry VandenDriessche, Marinee K. Chuah

Date : 01/10/2015 Item size : 834056 bytes

[...]from the very beginning, the nomenclature and the phenotype of EPCs have been subject to controversy and there are currently no specific markers that can unambiguously identify these ...

Cardiovascular Research, Review, Mette K. Hagensen, Paul M. Vanhoutte, Jacob F. Bentzon

Date : 01/08/2012 Item size : 445111 bytes

Uncontrolled collagen accumulation leads to arterial stenosis, while excessive collagen breakdown combined with inadequate synthesis weakens plaques thereby making them prone to rupture. Fibrillar ...

Cardiovascular Research, Review, Mark D. Rekhter

Date : 01/02/1999 Item size : 487429 bytes

[...]re-endothelialization is not always complete and often dysfunctional. [...]the molecular and biomechanical mechanisms that control EC repair and function in stented segments are poorly ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON BIOMECHANICAL FACTORS IN CARDIOVASCULAR DISEASE, Kim Van der Heiden, Frank J. H. Gijsen, Andrew Narracott, Sarah Hsiao, Ian Halliday, Julian ...

Date : 15/07/2013 Item size : 450524 bytes