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In the present study, we therefore searched for adenosine-induced changes in the expression of early genes in cultured human coronary artery smooth muscle cells (HCASMCs). Methods and results ...

Cardiovascular Research, Original Article, Peter Mayer, Annette Viktoria Hinze, Anja Harst, Ivar von Kügelgen

Date : 01/04/2011 Item size : 339812 bytes

Methods and results Human atherosclerotic carotid plaques (n = 24) were classified as non-haemorrhagic (NH) or haemorrhagic (Hem), according to their macroscopic aspect and haemoglobin ...

Cardiovascular Research, Original Article, Julien Le Dall, Benoît Ho-Tin-Noé, Liliane Louedec, Olivier Meilhac, Carmen Roncal, Peter Carmeliet, Stéphane Germain, Jean-Baptiste Michel, Xavier ...

Date : 01/01/2010 Item size : 302733 bytes

Resistin also significantly upregulated the mRNA expression of vascular endothelial growth factor receptors (VEGFR-1 and VEGFR-2) and matrix metalloproteinases (MMP-1 and MMP-2) at both mRNA and ...

Cardiovascular Research, Original Article, Hong Mu, Ryuji Ohashi, Shaoyu Yan, Hong Chai, Hui Yang, Peter Lin, Qizhi Yao, Changyi Chen

Date : 01/04/2006 Item size : 281449 bytes

Abstract Objective: To summarize the structure, function, and regulation of matrix metalloproteinases (MMPs) and to review the literature to date on their potential role in the pathogenesis of acute ...

Cardiovascular Research, Review, Charles B Jones, David C Sane, David M Herrington

Date : 01/10/2003 Item size : 533289 bytes

Abstract The discovery of the vascular endothelial growth factor (VEGF) family members VEGF, VEGF-B, placental growth factor (PlGF), VEGF-C and VEGF-D and their receptors VEGFR-1, -2 and -3 has ...

Cardiovascular Research, Review, Tuomas Tammela, Berndt Enholm, Kari Alitalo, Karri Paavonen

Date : 15/02/2005 Item size : 723617 bytes

Abstract Objective:: Transforming growth factor (TGF)-β promotes the deposition of extracellular matrix protein and also acts as an anti-inflammatory cytokine. Methods:: Anterior MI was produced ...

Cardiovascular Research, Research Article, Masaki Ikeuchi, Hiroyuki Tsutsui, Tetsuya Shiomi, Hidenori Matsusaka, Shouji Matsushima, Jing Wen, Toru Kubota, Akira Takeshita

Date : 01/12/2004 Item size : 252606 bytes

Abstract Objective: The concept of therapeutic angiogenesis with vascular endothelial growth factor (VEGF) has been validated in peripheral arterial disease. Various doses of recombinant VEGF or AIA ...

Cardiovascular Research, Original Article, Bernard Malavaud, Ivan Tack, Frédéric Jonca, Françoise Praddaude, Françoise Moro, Jean-Louis Ader, Jean Plouët

Date : 01/11/1997 Item size : 247534 bytes

[...]endothelial progenitor cells isolated from human peripheral blood showed enhanced VEGF expression and improved angiogenic activity in response to PKC activation. [...]incubation of HUVEC with ...

Cardiovascular Research, Original Article, Hui Xu, Petra Czerwinski, Marcus Hortmann, Hae-Young Sohn, Ulrich Förstermann, Huige Li

Date : 01/05/2008 Item size : 272686 bytes

Reviewed are endothelial Ca2+ stores, Ca2+ channels, and in-out-in Ca2+ signalling events, from ligand-binding on the plasma membrane into depletion of intracellular Ca2+ stores and therefrom out to ...

Cardiovascular Research, Review, Quang-Kim Tran, Kyoichi Ohashi, Hiroshi Watanabe

Date : 01/10/2000 Item size : 462205 bytes

Abstract Objective This study investigates whether local sequential delivery of vascular endothelial growth factor-A165 (VEGF-A165) followed by platelet-derived growth factor-BB (PDGF-BB) with ...

Cardiovascular Research, Original Article, Xiaojin Hao, Eduardo A. Silva, Agneta Månsson-Broberg, Karl-Henrik Grinnemo, Anwar J. Siddiqui, Göran Dellgren, Eva Wärdell, Lars Åke Brodin, ...

Date : 01/07/2007 Item size : 268555 bytes