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Ehjcardiovascrec

[...]current clinical trials using highly effective and selective inhibitors of STAT3 signalling for distinct diseases, such as myelofibrosis and rheumatoid arthritis, are discussed with regard to ...

Cardiovascular Research, Review, Jochen Dutzmann, Jan-Marcus Daniel, Johann Bauersachs, Denise Hilfiker-Kleiner, Daniel G. Sedding

Date : 01/06/2015 Item size : 659883 bytes
Ehjcardiovascrec

Results: AdCA5 increased the expression of HIF-1α, monocyte chemotactic protein-1, placental growth factor, platelet-derived growth factor B, stromal-derived factor 1α, and vascular endothelial ...

Cardiovascular Research, Original Article, Tarak H. Patel, Hideo Kimura, Clifford R. Weiss, Gregg L. Semenza, Lawrence V. Hofmann

Date : 01/10/2005 Item size : 273531 bytes
Ehjcardiovascrec

Methods and results We used a direct atrial myocytefibroblast contact co-culture and a fibroblast-specific transforming growth factor β1 (TGF-β1), connective tissue growth factor (CTGF) and ...

Cardiovascular Research, ORIGINAL ARTICLES: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Chia-Ti Tsai, Chuen-Den Tseng, Juey-Jen Hwang, Cho-Kai Wu, Chih-Chieh Yu, Yi-Chih Wang, Wen-Pin Chen, ...

Date : 01/03/2011 Item size : 286788 bytes
Ehjcardiovascrec

Within atherosclerotic lesions, Egr-1 is expressed in smooth muscle cells, endothelial cells, and macrophages. Since macrophages play a pivotal role in atherosclerotic lesion initiation and ...

Cardiovascular Research, Original Article, Claudia Albrecht, Michael R. Preusch, Götz Hofmann, Samuel Morris-Rosenfeld, Erwin Blessing, Michael E. Rosenfeld, Hugo A. Katus, Florian Bea

Date : 01/05/2010 Item size : 289814 bytes
Ehjcardiovascrec

Abstract Background: Furin-like proprotein convertases (PCs) are proteolytic activators of proproteins, like membrane type 1-matrix metalloproteinase (MT1-MMP) and transforming growth factor β ...

Cardiovascular Research, Original Article, Joost P.G. Sluijter, Robert E. Verloop, Wilco P.C. Pulskens, Evelyn Velema, Jos M. Grimbergen, Paul H. Quax, Marie-José Goumans, Gerard Pasterkamp, ...

Date : 01/10/2005 Item size : 270660 bytes
Ehjcardiovascrec

Methods and results We adapted a human EC spheroid model to examine PC effects on vascular endothelial growth factor-A-induced EC sprouting in vitro by using Bcl-2-transduced human umbilical vein ECs ...

Cardiovascular Research, Vascular biology, William G. Chang, Jillian W. Andrejecsk, Martin S. Kluger, W. Mark Saltzman, Jordan S. Pober

Date : 01/12/2013 Item size : 266541 bytes
Ehjcardiovascrec

Methods: CD34CD14+ monocytes were isolated from human peripheral blood by adherence separation and magnetic bead selection (purity <90%) and cultured on fibronectin-coated plastic dishes (medium ...

Cardiovascular Research, Original Article, Alexander Schmeisser, Christoph D. Garlichs, Hong Zhang, Saeed Eskafi, Christiane Graffy, Josef Ludwig, Ruth H. Strasser, Werner G. Daniel

Date : 16/02/2001 Item size : 246671 bytes
Ehjcardiovascrec

Methods: Forty-four rats underwent coronary ligation and, 14 days later, were randomly allocated to receive in-scar injections (5×106 cells/150 μL) of green fluorescent protein ...

Cardiovascular Research, Original Article, Onnik Agbulut, Manuel Mazo, Christophe Bressolle, María Gutierrez, Kasra Azarnoush, Laurent Sabbah, Nicolas Niederlander, Gloria Abizanda, Enrique J. ...

Date : 01/10/2006 Item size : 266867 bytes
Ehjcardiovascrec

Methods and results Using miRNA microarray, real-time PCR, and luciferase reporter assay, our study showed that miR-490-3p and insulin-like growth factor-1 (IGF1) expression were down-regulated, ...

Cardiovascular Research, Vascular biology, Yufa Sun, Deyou Chen, Lijuan Cao, Rongrong Zhang, Jie Zhou, Haiyan Chen, Yinyin Li, Minglong Li, Jian Cao, Zhe Wang

Date : 01/11/2013 Item size : 279466 bytes
Ehjcardiovascrec

Methods and results miR-214 is expressed in all major vascular cell types, and modulation of miR-214 levels in endothelial cells significantly affected tubular sprouting. Quaking knockdown reduced ...

Cardiovascular Research, ORIGINAL ARTICLES: FOCUS ON MICRORNA IN CARDIOVASCULAR BIOLOGY AND DISEASE, Alain van Mil, Sebastian Grundmann, Marie-José Goumans, Zhiyong Lei, Martinus I. Oerlemans, ...

Date : 15/03/2012 Item size : 283244 bytes