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Ehjcardiovascrec

[...]anti-fibrotic strategies are increasingly recognized as a promising approach in the prevention and treatment of heart failure. [...]dissecting the molecular mechanisms underlying the ...

Cardiovascular Research, Review, Esther E. Creemers, Yigal M. Pinto

Date : 01/02/2011 Item size : 426359 bytes
Ehjcardiovascrec

Abstract Objectives: Although heparin-binding epidermal growth factor-like growth factor (HB-EGF) is thought to produce hypertrophy in isolated cardiomyocytes via an autocrine mechanism, the ...

Cardiovascular Research, Original Article, Takayuki Fujino, Naoyuki Hasebe, Masaaki Fujita, Katsuro Takeuchi, Jun-ichi Kawabe, Katsuyuki Tobise, Shigeki Higashiyama, Naoyuki Taniguchi, Kenjiro Kikuchi

Date : 01/05/1998
Ehjcardiovascrec

While different cardiac pathologies have been targeted with cell therapy, most data come from experimental and clinical studies on stem cell transplantation into the failing, infarcted ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON HETEROCELLULAR SIGNALLING AND CROSSTALK IN THE HEART IN ISCHAEMIA AND HEART FAILURE, Arti A. Ramkisoensing, Antoine A.F. de Vries, Douwe E. ...

Date : 01/05/2014
Ehjcardiovascrec

Abstract Aims Our previous studies documented that Rad (Ras associated with diabetes), a member of the RGK (Rad, Gem, and Kir) family of Ras-related small G protein, is significantly decreased in ...

Cardiovascular Research, Original Article, Ji Zhang, Lin Chang, Chunlei Chen, Meiling Zhang, Yan Luo, Milton Hamblin, Luis Villacorta, Jing-Wei Xiong, Y. Eugene Chen, Jifeng Zhang, Xiaojun Zhu

Date : 01/07/2011
Ehjcardiovascrec

Metformin inhibited cardiac fibrosis (fibrosis area/total heart area: 0.6 ± 0.3 vs. 3.6 ± 0.9%, P < 0.01) induced by pressure overload and improved cardiac diastolic function (left ventricular ...

Cardiovascular Research, Original Article, Han Xiao, Xiaowei Ma, Wei Feng, Yongnan Fu, Zhizhen Lu, Ming Xu, Qiang Shen, Yi Zhu, Youyi Zhang

Date : 01/08/2010
Ehjcardiovascrec

Introduction Cardiac fibrosis is characterized by the expansion of the interstitial compartment caused by increased deposition of extracellular matrix (ECM) by activated myofibroblasts.1 In the ...

Cardiovascular Research, Original Article, Sashwati Roy, Savita Khanna, Ali Azad, Rebecca Schnitt, Guanglong He, Cora Weigert, Hidenori Ichijo, Chandan K. Sen

Date : 01/09/2010
Ehjcardiovascrec

Typical medication that helps systolic HF (HF with reduced EF, HFREF) patients, such as beta-blockade and angiotensin-converting enzyme inhibitors, are not successful in HFPEF patients.1 HFPEF is ...

Cardiovascular Research, Editorial, Dirk Westermann, Stephane Heymans

Date : 15/07/2014
Ehjcardiovascrec

Typical medication that helps systolic HF (HF with reduced EF, HFREF) patients, such as beta-blockade and angiotensin-converting enzyme inhibitors, are not successful in HFPEF patients.1 HFPEF is ...

Cardiovascular Research, Westermann, Dirk, Heymans, Stephane

Date : 15/07/2014 Item size : 153483 bytes
Ehjcardiovascrec

TGF-β is an important activator of chemokines and attracts monocytes into the heart.6 Micro-RNAs,7 plasminogen activator-inhibitor 1,8 or non-canonical, SMAD-independent activation of junction ...

Cardiovascular Research, Fabritz, Larissa, Kirchhof, Paulus

Date : 01/09/2013
Ehjcardiovascrec

Abstract Aims Our previous studies documented that Rad (Ras associated with diabetes), a member of the RGK (Rad, Gem, and Kir) family of Ras-related small G protein, is significantly decreased in ...

Cardiovascular Research, Zhang, Ji, Chang, Lin, Chen, Chunlei, Zhang, Meiling, Luo, Yan, Hamblin, Milton, Villacorta, Luis, Xiong, Jing-Wei, Chen, Y. Eugene, Zhang, Jifeng, Zhu, Xiaojun

Date : 01/07/2011 Item size : 314026 bytes