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Growing evidence suggests differences between these two cardiac endothelial cell types with regard to developmental, morphological and functional properties. KeywordsEndocardial endotheliumVascular ...

Cardiovascular Research, Review, Dirk L. Brutsaert, Paul Fransen, Luc J. Andries, Gilles W. De Keulenaer, Stanislas U. Sys

Date : 01/05/1998 Item size : 304791 bytes

Abstract Objective This study investigates whether local sequential delivery of vascular endothelial growth factor-A165 (VEGF-A165) followed by platelet-derived growth factor-BB (PDGF-BB) with ...

Cardiovascular Research, Original Article, Xiaojin Hao, Eduardo A. Silva, Agneta Månsson-Broberg, Karl-Henrik Grinnemo, Anwar J. Siddiqui, Göran Dellgren, Eva Wärdell, Lars Åke Brodin, ...

Date : 01/07/2007 Item size : 268555 bytes

[...]anti-fibrotic strategies are increasingly recognized as a promising approach in the prevention and treatment of heart failure. [...]dissecting the molecular mechanisms underlying the ...

Cardiovascular Research, Review, Esther E. Creemers, Yigal M. Pinto

Date : 01/02/2011 Item size : 426359 bytes

Abstract Aims Cells derived from the stroma vascular fraction (SVF) of mouse adipose tissue can spontaneously give rise to rare, functional, cardiac-like cells in vitro. Methods and results The ...

Cardiovascular Research, Original Article, Bertrand Léobon, Jérôme Roncalli, Carine Joffre, Manuel Mazo, Marie Boisson, Corinne Barreau, Denis Calise, Emmanuelle Arnaud, Mireille André, ...

Date : 01/09/2009

Various cell types have been successfully employed in the recovery of cardiac damage by reducing inflammation, activating endogenous regenerative responses, and, in some cases, directly participating ...

Cardiovascular Research, Cardiac biology and remodelling, Dries Feyen, Roberto Gaetani, Jia Liu, Willy Noort, Anton Martens, Krista den Ouden, Pieter A. Doevendans, Joost P.G. Sluijter

Date : 01/07/2013

[...]EPO increases VEGF expression in various ischaemic tissues and cardiac VEGF levels are strongly correlated with new vessel formation.811 Secondly, EPO only stimulates neovascularization in the ...

Cardiovascular Research, Original Article, B. Daan Westenbrink, Willem-Peter T. Ruifrok, Adriaan A. Voors, Ronald G. Tilton, Dirk J. van Veldhuisen, Regien G. Schoemaker, Wiek H. van Gilst, Rudolf A. ...

Date : 01/07/2010

Cardiac stem cells with electrical stimulation improve ischaemic heart function through regulation of connective tissue growth factor and miR-378 Abstract Aims In this study, we investigated whether ...

Cardiovascular Research, Original Article, Sun Wook Kim, Ha Won Kim, Wei Huang, Motoi Okada, Jeffrey A. Welge, Yigang Wang, Muhammad Ashraf

Date : 01/11/2013

Metformin inhibited cardiac fibrosis (fibrosis area/total heart area: 0.6 ± 0.3 vs. 3.6 ± 0.9%, P < 0.01) induced by pressure overload and improved cardiac diastolic function (left ventricular ...

Cardiovascular Research, Original Article, Han Xiao, Xiaowei Ma, Wei Feng, Yongnan Fu, Zhizhen Lu, Ming Xu, Qiang Shen, Yi Zhu, Youyi Zhang

Date : 01/08/2010

To uncover novel therapeutics for heart failure (HF), attention has focussed on the biological factors that underlie the transition from an initially adaptive hypertrophic response to a maladaptive ...

Cardiovascular Research, Editorial, Tariq Hamid, Sumanth D. Prabhu

Date : 01/07/2010

Table 1 summarises phase II angiogenesis gene therapy trials that have been completed for both coronary and peripheral artery disease. [...]angiogenesis gene therapy has quietly reached the era of ...

Cardiovascular Research, Editorial, Sigrid Nikol

Date : 01/02/2007