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Ehjcardiovascrec

Abstract Cardiac hypertrophy and fibrosis are two closely related adaptive response mechanisms of the myocardium to mechanical, metabolic, and genetic stress that finally contribute to the ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON HETEROCELLULAR SIGNALLING AND CROSSTALK IN THE HEART IN ISCHAEMIA AND HEART FAILURE, Janika Viereck, Claudia Bang, Ariana Foinquinos, Thomas ...

Date : 01/05/2014 Item size : 769285 bytes
Ehjcardiovascrec

[...]when cultured in the 3D-collagen gel system, FGF-induced p38 MAPK activation regulates tubulogenesis by possibly increasing apoptosis.4,5 Moreover, FGFs can induce cell-cycle arrest, ...

Cardiovascular Research, Review, Masahiro Murakami, Arye Elfenbein, Michael Simons

Date : 01/05/2008 Item size : 436433 bytes
Ehjcardiovascrec

miRNAs influence key physiological processes, such as proliferation, migration, differentiation, secretion, excitation, conduction, cell cycle, and apoptosis, by altering protein expression of ...

Cardiovascular Research, REVIEWS: FOCUS ON MICRORNA IN CARDIOVASCULAR BIOLOGY AND DISEASE, S. Dangwal, C. Bang, T. Thum

Date : 15/03/2012 Item size : 441676 bytes
Ehjcardiovascrec

[...]current clinical trials using highly effective and selective inhibitors of STAT3 signalling for distinct diseases, such as myelofibrosis and rheumatoid arthritis, are discussed with regard to ...

Cardiovascular Research, Review, Jochen Dutzmann, Jan-Marcus Daniel, Johann Bauersachs, Denise Hilfiker-Kleiner, Daniel G. Sedding

Date : 01/06/2015 Item size : 659883 bytes
Ehjcardiovascrec

Methods and results We adapted a human EC spheroid model to examine PC effects on vascular endothelial growth factor-A-induced EC sprouting in vitro by using Bcl-2-transduced human umbilical vein ECs ...

Cardiovascular Research, Vascular biology, William G. Chang, Jillian W. Andrejecsk, Martin S. Kluger, W. Mark Saltzman, Jordan S. Pober

Date : 01/12/2013 Item size : 266541 bytes
Ehjcardiovascrec

Abstract Objective Id2 (inhibitor of DNA-binding 2), a member of the helixloophelix family of transcription regulators, plays important roles in cell proliferation and ...

Cardiovascular Research, Original Article, Xiaojun Zhu, Yiming Lin, Methode Bacanamwo, Lin Chang, Rui Chai, Ivana Massud, Jifeng Zhang, Minerva T. Garcia-Barrio, Winston E. Thompson, Yuqing E. Chen

Date : 01/10/2007 Item size : 260050 bytes
Ehjcardiovascrec

Recently, the resident macrophage is considered to have vital functions in the maintenance of tissues and homeostasis in many organs, including brain, liver, adipose tissue, lymphatic tissue, and ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON HETEROCELLULAR SIGNALLING AND CROSSTALK IN THE HEART IN ISCHAEMIA AND HEART FAILURE, Katsuhito Fujiu, Jack Wang, Ryozo Nagai

Date : 01/05/2014 Item size : 404798 bytes
Ehjcardiovascrec

HIF-1 consists of O2-regulated HIF-1α and constitutively expressed HIF-1β subunits.1 HIF-2α is a HIF-1α paralogue that is also involved in vascular responses to ischaemia.2,3 In humans, ...

Cardiovascular Research, SPOTLIGHT REVIEWS, Sergio Rey, Gregg L. Semenza

Date : 01/05/2010 Item size : 454352 bytes
Ehjcardiovascrec

[...]this ligandreceptor pair promotes cardiomyocyte survival, neovascularization, and cardiac function after myocardial infarction (MI).19 The SDF-1/CXCR4 axis plays a crucial role during embryonic ...

Cardiovascular Research, Review, Chiara Cencioni, Maurizio C. Capogrossi, Monica Napolitano

Date : 01/06/2012 Item size : 571264 bytes
Ehjcardiovascrec

[...]research focused on FGF-2 has revealed an important place for this protein in cardiac cells in health and disease. Despite its name, FGF-2 is now known to modulate numerous cellular functions ...

Cardiovascular Research, Review, Karen A. Detillieux, Farah Sheikh, Elissavet Kardami, Peter A. Cattini

Date : 01/01/2003 Item size : 588995 bytes