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Ehjcardiovascrec

[...]current clinical trials using highly effective and selective inhibitors of STAT3 signalling for distinct diseases, such as myelofibrosis and rheumatoid arthritis, are discussed with regard to ...

Cardiovascular Research, Review, Jochen Dutzmann, Jan-Marcus Daniel, Johann Bauersachs, Denise Hilfiker-Kleiner, Daniel G. Sedding

Date : 01/06/2015 Item size : 659883 bytes
Ehjcardiovascrec

Furthermore, the biological significance of the COX-2 gene in endothelial cells was examined by over-expressing or knocking down COX-2 gene expression. 3H-Thymidine incorporation and Matrigel ...

Cardiovascular Research, Original Article, GuiFu Wu, Jincai Luo, Jamal S. Rana, Roger Laham, Frank W. Sellke, Jian Li

Date : 01/02/2006 Item size : 210338 bytes
Ehjcardiovascrec

Arrhythmogenic right ventricular dysplasia type 1 and mutations in transforming growth factor β3 gene regulatory regions: a breakthrough? Arrhythmogenic right ventricular dysplasia (ARVD) is the ...

Cardiovascular Research, Editorial, Stanley Nattel, Jean-Jacques Schott

Date : 01/02/2005 Item size : 199393 bytes
Ehjcardiovascrec

The platelet-derived growth factor (PDGF) BB is recognized as a major migratory factor for arterial SMCs both in vitro and during neointima formation. Since PDGF acts in synergy with the matrix ...

Cardiovascular Research, Original Article, Sandra Jalvy, Marie-Ange Renault, Laetitia Lam Shang Leen, Isabelle Belloc, Jacques Bonnet, Alain-Pierre Gadeau, Claude Desgranges

Date : 01/09/2007 Item size : 325661 bytes
Ehjcardiovascrec

Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death Abstract Objective: The signaling pathways ...

Cardiovascular Research, Original Article, Frank Jung, Judith Haendeler, Christine Goebel, Andreas M. Zeiher, Stefanie Dimmeler

Date : 01/10/2000
Ehjcardiovascrec

Abstract Aims Resveratrol (RV), an antioxidant, inhibits angiotensin II (Ang II)-induced hypertrophy and Ang II- or epidermal growth factor (EGF)-induced Akt phosphorylation in rat vascular smooth ...

Cardiovascular Research, Original Article, Cornelia E. Schreiner, Mario Kumerz, Julia Gesslbauer, Daniel Schachner, Helge Joa, Thomas Erker, Atanas G. Atanasov, Elke H. Heiss, Verena M. Dirsch

Date : 01/04/2011
Ehjcardiovascrec

Prorenin binds PRR three times more efficiently than renin,2,3 and after the binding its catalytic site is unmasked, resulting in a full activation of this pro-enzyme.4 The binding of prorenin to the ...

Cardiovascular Research, Original Article, Carolina M. Greco, Marina Camera, Laura Facchinetti, Marta Brambilla, Sara Pellegrino, Maria Luisa Gelmi, Elena Tremoli, Alberto Corsini, Nicola Ferri

Date : 01/08/2012
Ehjcardiovascrec

Abstract Objectives: Platelet-derived growth factor (PDGF) stimulates growth in various types of cells, but little is known about its effect on cardiac myocytes. [...]we examined whether PDGF had a ...

Cardiovascular Research, Original Article, Tatsuya Shimizu, Koh-ichiro Kinugawa, Atsushi Yao, Yasuyuki Sugishita, Kazuro Sugishita, Kazumasa Harada, Hiroshi Matsui, Osami Kohmoto, Takashi Serizawa, ...

Date : 01/03/1999
Ehjcardiovascrec

Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells Abstract Aims Abnormal migration and ...

Cardiovascular Research, Original Article, Keun Hwa Choi, Jong-Eun Kim, Nu Ry Song, Joe Eun Son, Mun Kyung Hwang, Sanguine Byun, Jong Hun Kim, Ki Won Lee, Hyong Joo Lee

Date : 01/03/2010
Ehjcardiovascrec

[...]current clinical trials using highly effective and selective inhibitors of STAT3 signalling for distinct diseases, such as myelofibrosis and rheumatoid arthritis, are discussed with regard to ...

Cardiovascular Research, Dutzmann, Jochen, Daniel, Jan-Marcus, Bauersachs, Johann, Hilfiker-Kleiner, Denise, Sedding, Daniel G.

Date : 01/06/2015 Item size : 512523 bytes