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Ehjcardiovascrec

Methods and results We used a direct atrial myocytefibroblast contact co-culture and a fibroblast-specific transforming growth factor β1 (TGF-β1), connective tissue growth factor (CTGF) and ...

Cardiovascular Research, ORIGINAL ARTICLES: FOCUS ON THE MOLECULAR BASIS OF ATRIAL FIBRILLATION, Chia-Ti Tsai, Chuen-Den Tseng, Juey-Jen Hwang, Cho-Kai Wu, Chih-Chieh Yu, Yi-Chih Wang, Wen-Pin Chen, ...

Date : 01/03/2011 Item size : 286788 bytes
Ehjcardiovascrec

Introduction Human embryonic stem cells (hESCs), which are derived from the inner cell mass of a blastocyst, have a high self-renewal capacity and the potential to differentiate into all three germ ...

Cardiovascular Research, Vascular biology, Sun-Hwa Song, Kyungjong Kim, Jeong Joo Park, Kyung Hoon Min, Wonhee Suh

Date : 01/07/2014 Item size : 269820 bytes
Ehjcardiovascrec

Reactive oxygen species (ROS) such as superoxide and H2O2 function as signaling molecules in many aspects of growth factor-mediated responses including angiogenesis. Vascular endothelial growth ...

Cardiovascular Research, Review, Masuko Ushio-Fukai

Date : 15/07/2006 Item size : 528604 bytes
Ehjcardiovascrec

[...]latest insights into the role of cardiac fibroblasts in the orchestration of inflammatory cell infiltration in the heart, and their impact on heart failure, are outlined. [...]fibrosis leads to ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON HETEROCELLULAR SIGNALLING AND CROSSTALK IN THE HEART IN ISCHAEMIA AND HEART FAILURE, Sophie Van Linthout, Kapka Miteva, Carsten Tschöpe

Date : 01/05/2014
Ehjcardiovascrec

In the experimental newborn calf model of hypoxia-induced PH, adventitial fibroblasts in the PA wall exhibit a heightened replication index. Because elevated platelet-derived growth factor β ...

Cardiovascular Research, Original Article, Evgeniy Panzhinskiy, W. Michael Zawada, Kurt R. Stenmark, Mita Das

Date : 01/08/2012
Ehjcardiovascrec

Abstract Aims Resveratrol (RV), an antioxidant, inhibits angiotensin II (Ang II)-induced hypertrophy and Ang II- or epidermal growth factor (EGF)-induced Akt phosphorylation in rat vascular smooth ...

Cardiovascular Research, Original Article, Cornelia E. Schreiner, Mario Kumerz, Julia Gesslbauer, Daniel Schachner, Helge Joa, Thomas Erker, Atanas G. Atanasov, Elke H. Heiss, Verena M. Dirsch

Date : 01/04/2011
Ehjcardiovascrec

Abstract Aims We have recently shown that urokinase plasminogen activator (uPA) increases oxidative stress (OS), cholesterol biosynthesis, and paraoxonase 2 (PON2) expression in macrophages via ...

Cardiovascular Research, Original Article, Bianca Fuhrman, Anna Gantman, Jasmin Khateeb, Nina Volkova, Sven Horke, Julia Kiyan, Inna Dumler, Michael Aviram

Date : 01/10/2009
Ehjcardiovascrec

Insulin-like growth factor-I induces reactive oxygen species production and cell migration through Nox4 and Rac1 in vascular smooth muscle cells Abstract Aims We showed previously that insulin-like ...

Cardiovascular Research, Original Article, Dan Meng, Dan-Dan Lv, Jing Fang

Date : 01/11/2008
Ehjcardiovascrec

Abstract Objective Reactive oxygen species (ROS) produced by NAD(P)H oxidases (Nox) play a significant role in the pathophysiology of cardiovascular diseases. Preincubation with VAS2870 (10 and 20 ...

Cardiovascular Research, Original Article, Henrik ten Freyhaus, Michael Huntgeburth, Kirstin Wingler, Jessika Schnitker, Anselm T. Bäumer, Marius Vantler, Mohamed M. Bekhite, Maria Wartenberg, ...

Date : 15/07/2006
Ehjcardiovascrec

Abstract Objective: We previously showed that mitochondrial coupling factor 6 (CF6), an endogenous inhibitor of prostacyclin synthesis and a vasoconstrictor, is present on the surface of human ...

Cardiovascular Research, Original Article, Hirofumi Tomita, Tomohiro Osanai, Tsutomu Toki, Satoko Sasaki, Naotaka Maeda, Reiichi Murakami, Koji Magota, Minoru Yasujima, Ken Okumura

Date : 01/07/2005