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[...]when cultured in the 3D-collagen gel system, FGF-induced p38 MAPK activation regulates tubulogenesis by possibly increasing apoptosis.4,5 Moreover, FGFs can induce cell-cycle arrest, ...

Cardiovascular Research, Review, Masahiro Murakami, Arye Elfenbein, Michael Simons

Date : 01/05/2008 Item size : 436433 bytes

Vascular endothelial growth factor (VEGF), also known as VEGF-A to distinguish it from other isoforms (BD) that are mainly involved in lymphangiogenesis, is an endothelial cell mitogen that has an ...

Cardiovascular Research, Editorial, Rosalinda Madonna, Raffaele De Caterina

Date : 01/10/2009 Item size : 187778 bytes

Abstract Objective: Here we investigated the role of spleen tyrosine kinase (Syk) in the migration induced by platelet-derived growth factor (PDGF) in rat aortic smooth muscle cells (RASMC). A ...

Cardiovascular Research, Original Article, Chang-Kwon Lee, Hwan Myung Lee, Hyo Jin Kim, Hyo-Jun Park, Kyung-Jong Won, Hui Yul Roh, Wahn Soo Choi, Byeong Hwa Jeon, Tae-Kyu Park, Bokyung Kim

Date : 01/04/2007 Item size : 281855 bytes

Abstract Cell communication, an essential component of integrated physiological function in multicellular organisms, is mediated largely through informational molecules, such as hormones and ...

Cardiovascular Research, Review, Andreas Goette, Uwe Lendeckel, Helmut U Klein

Date : 01/05/2002 Item size : 494477 bytes

To understand the concept of growth factor dysfunction, it is important to briefly review the ordinary function of growth factors, their receptors, and their intracellular downstream machinery; both ...

Cardiovascular Research, Review, Johannes Waltenberger

Date : 15/02/2005

Abstract Aims Abnormal migration of human aortic smooth muscle cells (HASMCs) causes intimal thickening of the aorta, a pivotal step in atherosclerotic development. Methods and results We analysed ...

Cardiovascular Research, Vascular biology, Joe Eun Son, Eunjung Lee, Sung Keun Jung, Jong Eun Kim, Min-Ho Oak, Ki Won Lee, Hyong Joo Lee

Date : 01/03/2014

When the Nobel prize for physiology and medicine was awarded for the discovery of the first peptide growth factors to Rita Levi-Montalcini and Stanley Cohen in 1986, Russel Ross in Seattle was among ...

Cardiovascular Research, Editorial, Mark Post, Johannes Waltenberger

Date : 15/02/2005

Methods and results All red wines concentration dependently inhibited the ligand-induced tyrosine phosphorylation of the PDGFR, downstream signalling events such as mitogen activated protein (MAP) ...

Cardiovascular Research, Original Article, Jan Sparwel, Marius Vantler, Evren Caglayan, Kai Kappert, Jochen W.U. Fries, Helmut Dietrich, Michael Böhm, Erland Erdmann, Stephan Rosenkranz

Date : 01/03/2009

The latter act as second messengers to activate critical kinase cascades that trigger entrance into the preconditioned state. [...]NO exposure before ischemia can act as a powerful preconditioning ...

Cardiovascular Research, Review, Michael V. Cohen, Xi-Ming Yang, James M. Downey

Date : 01/05/2006

In early-stage development of adipose tissue, adipogenesis is tightly associated with angiogenesis. [...]adipose tissue explants trigger blood vessel formation, and in turn adipose tissue ...

Cardiovascular Research, Review, H. Roger Lijnen

Date : 01/05/2008