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Studies in small and large animal ischaemic heart disease models have reported that myocardial overexpression of VEGF following naked DNA transfection, Ad vectors, or AAV transduction induce ...

Cardiovascular Research, Review, Melvin Y. Rincon, Thierry VandenDriessche, Marinee K. Chuah

Date : 01/10/2015 Item size : 834056 bytes

The demonstration that gene therapy can improve collateral function presents one of the solutions to the conundrum, since gene therapy can be considered a sophisticated form of a sustained delivery ...

Cardiovascular Research, Review, Stephen E. Epstein, Shmuel Fuchs, Yi Fu Zhou, Richard Baffour, Ran Kornowski

Date : 16/02/2001 Item size : 488164 bytes

Abstract Aims The objectives of this study are to determine the role of response gene to complement 32 (RGC-32) in the placental angiogenesis during pregnancy and explore the underlying ...

Cardiovascular Research, Original Article, Xiao-Bing Cui, Xia Guo, Shi-You Chen

Date : 01/09/2013 Item size : 306938 bytes

Methods and results Human atherosclerotic carotid plaques (n = 24) were classified as non-haemorrhagic (NH) or haemorrhagic (Hem), according to their macroscopic aspect and haemoglobin ...

Cardiovascular Research, Original Article, Julien Le Dall, Benoît Ho-Tin-Noé, Liliane Louedec, Olivier Meilhac, Carmen Roncal, Peter Carmeliet, Stéphane Germain, Jean-Baptiste Michel, Xavier ...

Date : 01/01/2010 Item size : 302733 bytes

Resistin also significantly upregulated the mRNA expression of vascular endothelial growth factor receptors (VEGFR-1 and VEGFR-2) and matrix metalloproteinases (MMP-1 and MMP-2) at both mRNA and ...

Cardiovascular Research, Original Article, Hong Mu, Ryuji Ohashi, Shaoyu Yan, Hong Chai, Hui Yang, Peter Lin, Qizhi Yao, Changyi Chen

Date : 01/04/2006 Item size : 281449 bytes

Abstract The discovery of the vascular endothelial growth factor (VEGF) family members VEGF, VEGF-B, placental growth factor (PlGF), VEGF-C and VEGF-D and their receptors VEGFR-1, -2 and -3 has ...

Cardiovascular Research, Review, Tuomas Tammela, Berndt Enholm, Kari Alitalo, Karri Paavonen

Date : 15/02/2005 Item size : 723617 bytes

Abstract Objective: The concept of therapeutic angiogenesis with vascular endothelial growth factor (VEGF) has been validated in peripheral arterial disease. Various doses of recombinant VEGF or AIA ...

Cardiovascular Research, Original Article, Bernard Malavaud, Ivan Tack, Frédéric Jonca, Françoise Praddaude, Françoise Moro, Jean-Louis Ader, Jean Plouët

Date : 01/11/1997 Item size : 247534 bytes

[...]endothelial progenitor cells isolated from human peripheral blood showed enhanced VEGF expression and improved angiogenic activity in response to PKC activation. [...]incubation of HUVEC with ...

Cardiovascular Research, Original Article, Hui Xu, Petra Czerwinski, Marcus Hortmann, Hae-Young Sohn, Ulrich Förstermann, Huige Li

Date : 01/05/2008 Item size : 272686 bytes

Results: AdCA5 increased the expression of HIF-1α, monocyte chemotactic protein-1, placental growth factor, platelet-derived growth factor B, stromal-derived factor 1α, and vascular endothelial ...

Cardiovascular Research, Original Article, Tarak H. Patel, Hideo Kimura, Clifford R. Weiss, Gregg L. Semenza, Lawrence V. Hofmann

Date : 01/10/2005 Item size : 273531 bytes

Methods and results We adapted a human EC spheroid model to examine PC effects on vascular endothelial growth factor-A-induced EC sprouting in vitro by using Bcl-2-transduced human umbilical vein ECs ...

Cardiovascular Research, Vascular biology, William G. Chang, Jillian W. Andrejecsk, Martin S. Kluger, W. Mark Saltzman, Jordan S. Pober

Date : 01/12/2013 Item size : 266541 bytes