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In the present study, we therefore searched for adenosine-induced changes in the expression of early genes in cultured human coronary artery smooth muscle cells (HCASMCs). Methods and results ...

Cardiovascular Research, Original Article, Peter Mayer, Annette Viktoria Hinze, Anja Harst, Ivar von Kügelgen

Date : 01/04/2011 Item size : 339812 bytes

Methods and results Using miRNA microarray, real-time PCR, and luciferase reporter assay, our study showed that miR-490-3p and insulin-like growth factor-1 (IGF1) expression were down-regulated, ...

Cardiovascular Research, Vascular biology, Yufa Sun, Deyou Chen, Lijuan Cao, Rongrong Zhang, Jie Zhou, Haiyan Chen, Yinyin Li, Minglong Li, Jian Cao, Zhe Wang

Date : 01/11/2013 Item size : 279466 bytes

Abstract Objective Id2 (inhibitor of DNA-binding 2), a member of the helixloophelix family of transcription regulators, plays important roles in cell proliferation and ...

Cardiovascular Research, Original Article, Xiaojun Zhu, Yiming Lin, Methode Bacanamwo, Lin Chang, Rui Chai, Ivana Massud, Jifeng Zhang, Minerva T. Garcia-Barrio, Winston E. Thompson, Yuqing E. Chen

Date : 01/10/2007 Item size : 260050 bytes

Since the 1970's a link between infectious disease and atherosclerotic disease has been hypothesized [13]. Infectious agents that are implicated in the pathogenesis of atherosclerosis include ...

Cardiovascular Research, Editorial, Marcel Levi

Date : 01/06/2001 Item size : 156327 bytes

The incidence of plaque rupture and thrombotic events is largely correlated with specific morphological and histological features described for unstable plaques [1]. The structural components of ...

Cardiovascular Research, Review, Isabelle Gorenne, Mary Kavurma, Stephen Scott, Martin Bennett

Date : 01/10/2006 Item size : 478974 bytes

Abstract Objective: Here we investigated the role of spleen tyrosine kinase (Syk) in the migration induced by platelet-derived growth factor (PDGF) in rat aortic smooth muscle cells (RASMC). A ...

Cardiovascular Research, Original Article, Chang-Kwon Lee, Hwan Myung Lee, Hyo Jin Kim, Hyo-Jun Park, Kyung-Jong Won, Hui Yul Roh, Wahn Soo Choi, Byeong Hwa Jeon, Tae-Kyu Park, Bokyung Kim

Date : 01/04/2007 Item size : 281855 bytes

Abstract Objectives: Although heparin-binding epidermal growth factor-like growth factor (HB-EGF) is thought to produce hypertrophy in isolated cardiomyocytes via an autocrine mechanism, the ...

Cardiovascular Research, Original Article, Takayuki Fujino, Naoyuki Hasebe, Masaaki Fujita, Katsuro Takeuchi, Jun-ichi Kawabe, Katsuyuki Tobise, Shigeki Higashiyama, Naoyuki Taniguchi, Kenjiro Kikuchi

Date : 01/05/1998

Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death Abstract Objective: The signaling pathways ...

Cardiovascular Research, Original Article, Frank Jung, Judith Haendeler, Christine Goebel, Andreas M. Zeiher, Stefanie Dimmeler

Date : 01/10/2000

[...]the increase in the expression of proliferating cell nuclear antigen in the neointima was more significant and maintained longer in old rats than in the young ones. [...]the expression of ...

Cardiovascular Research, ORIGINALS, Xiaojing Wu, Qi Zhou, Lan Huang, Aijun Sun, Keqiang Wang, Yunzeng Zou, Junbo Ge

Date : 01/03/2008

Short-term treatment of spontaneously hypertensive rats with liver growth factor reduces carotid artery fibrosis, improves vascular function, and lowers blood pressure When compared to those of ...

Cardiovascular Research, Original Article, Beatriz Somoza, Fatima Abderrahim, José M. González, M. Victoria Conde, Silvia M. Arribas, Barry Starcher, Javier Regadera, María S. ...

Date : 15/02/2006