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Ehjcardiovascrec

[...]in the mouse model, histological determination of myocyte diameter, heart weight/body weight ratio, and echocardiographic measurements revealed that myocardial expression of DYRK1A failed to ...

Cardiovascular Research, Original Article, Cornelia Grebe, Theda-Maria Klingebiel, Simon Philipp Grau, Karl Toischer, Michael Didié, Claudius Jacobshagen, Christian Dullin, Gerd Hasenfuss, Tim ...

Date : 01/06/2011 Item size : 265108 bytes
Ehjcardiovascrec

KeywordsArrhythmia (mechanisms)Contractile functionHeart failureNa/Ca-exchangerSarcolemmaTime for primary review 21 days. 1 Introduction Sarcolemmal Na+Ca2+ exchange plays a pivotal role in ion ...

Cardiovascular Research, Review, Wolfgang Schillinger, Jan W Fiolet, Klaus Schlotthauer, Gerd Hasenfuss

Date : 15/03/2003 Item size : 515169 bytes
Ehjcardiovascrec

Abstract The progress made in our understanding of the pathophysiology and treatment of congestive heart failure (CHF) would not have been possible without a number of animal models of heart failure ...

Cardiovascular Research, Review, Gerd Hasenfuss

Date : 01/07/1998
Ehjcardiovascrec

Na+–Ca2+ exchanger overexpression predisposes to reactive oxygen species-induced injury Abstract Objective: In heart failure (HF), the generation of reactive oxygen species (ROS) is ...

Cardiovascular Research, Original Article, Stefan Wagner, Tim Seidler, Eckard Picht, Lars S Maier, Victor Kazanski, Nils Teucher, Wolfgang Schillinger, Burkert Pieske, Gerrit Isenberg, Gerd ...

Date : 01/11/2003
Ehjcardiovascrec

Abstract Background: Pyruvate has been shown to increase contractile function in isolated myocardium and to improve hemodynamics in patients with congestive heart failure. Conclusion: A combination ...

Cardiovascular Research, Original Article, Hans-Peter Hermann, Oliver Zeitz, Stephan E Lehnart, Boris Keweloh, Nicolin Datz, Gerd Hasenfuss, Paul M.L Janssen

Date : 01/01/2002
Ehjcardiovascrec

Notably, I-1-KO were partially protected from lethal catecholamine-induced arrhythmias and from hypertrophy and dilation induced by a 7 day infusion with the β-adrenergic agonist ...

Cardiovascular Research, Original Article, Ali El-Armouche, Katrin Wittköpper, Franziska Degenhardt, Florian Weinberger, Michael Didié, Ivan Melnychenko, Michael Grimm, Micha Peeck, Wolfram H. ...

Date : 01/12/2008
Ehjcardiovascrec

Defective EC-coupling in heart failure may result from altered density or function of proteins relevant for calcium homeostasis. Knowledge of these alterations is a prerequisite for understanding ...

Cardiovascular Research, Review, Gerd Hasenfuss

Date : 01/02/1998
Ehjcardiovascrec

Methods: Subepicardial (epi), midmyocardial (mid), and subendocardial (endo) sections of the left ventricular free wall from end-stage failing (n=17) and nonfailing (n=5) human hearts were analyzed ...

Cardiovascular Research, Original Article, Jürgen Prestle, Sabine Dieterich, Michael Preuss, Ursula Bieligk, Gerd Hasenfuss

Date : 01/08/1999
Ehjcardiovascrec

Abstract Objective: Increased levels of inhibitory G proteins have been observed in heart failure, but their physiological relevance in mediating the reduced β-adrenergic response is largely ...

Cardiovascular Research, Original Article, Paul M.L Janssen, Wolfgang Schillinger, J.Kevin Donahue, Oliver Zeitz, Shahriyar Emami, Stephan E Lehnart, Joachim Weil, Thomas Eschenhagen, Gerd Hasenfuss, ...

Date : 01/08/2002