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Ehjcardiovascrec

Abstract Objective: The cardiac ankyrin repeat protein (CARP), a nuclear transcription co-factor that negatively regulates cardiac gene expression, is increased in human heart failure and in animal ...

Cardiovascular Research, Original Article, Oliver Zolk, Michael Marx, Elmar Jäckel, Ali El-Armouche, Thomas Eschenhagen

Date : 01/09/2003 Item size : 258892 bytes
Ehjcardiovascrec

Methods: The effect of various preload conditions (2.515 mN) on force development was studied in right ventricular trabeculae carneae from explanted human failing hearts with ischemic cardiomyopathy ...

Cardiovascular Research, Original Article, Joachim Weil, Thomas Eschenhagen, Stefan Hirt, Olaf Magnussen, Clemens Mittmann, Ute Remmers, Hasso Scholz

Date : 01/02/1998 Item size : 278533 bytes
Ehjcardiovascrec

Importantly, neither the β-AR density nor the PP-1c protein levels differed from wild-type littermates, indicating no obvious major compensatory changes in the I-1 KO hearts.46,78 Moreover, ...

Cardiovascular Research, Review, Katrin Wittköpper, Dobromir Dobrev, Thomas Eschenhagen, Ali El-Armouche

Date : 01/08/2011 Item size : 468593 bytes
Ehjcardiovascrec

The central assumption underlying the concept of modelling cardiomyopathies in vitro is that the phenotype seen in patients has its correlate in the pathology of isolated cardiac myocyte or heart ...

Cardiovascular Research, INVITED SPOTLIGHT REVIEWS, Thomas Eschenhagen, Christine Mummery, Bjorn C. Knollmann

Date : 01/04/2015 Item size : 759955 bytes
Ehjcardiovascrec

Notably, I-1-KO were partially protected from lethal catecholamine-induced arrhythmias and from hypertrophy and dilation induced by a 7 day infusion with the β-adrenergic agonist ...

Cardiovascular Research, Original Article, Ali El-Armouche, Katrin Wittköpper, Franziska Degenhardt, Florian Weinberger, Michael Didié, Ivan Melnychenko, Michael Grimm, Micha Peeck, Wolfram H. ...

Date : 01/12/2008
Ehjcardiovascrec

Abstract Objective: The mitogen-activated kinase kinases (MEK)-extracellular signal-regulated kinases (ERK) signaling pathway is activated by agonists like catecholamines or endothelin-1 (ET-1) and ...

Cardiovascular Research, Original Article, Felix Münzel, Ulrike Mühlhäuser, Wolfram-Hubertus Zimmermann, Michael Didié, Karin Schneiderbanger, Pia Schubert, Sven Engmann, Thomas ...

Date : 01/12/2005
Ehjcardiovascrec

Abstract Objective: To characterize the cardiac angiotensin and endothelin (ET) system in compensated left ventricular hypertrophy due to long standing arterial hypertension and to assess the role of ...

Cardiovascular Research, Original Article, Oliver Zolk, Jessika Quattek, Ute Seeland, Ali El-Armouche, Thomas Eschenhagen, Michael Böhm

Date : 01/02/2002
Ehjcardiovascrec

The present article summarizes early and novel findings that, in the view of the authors, provide solid evidence for Gαi to play an important role in the adaptation of cardiac AC to various ...

Cardiovascular Research, Review, Ali El-Armouche, Oliver Zolk, Thomas Rau, Thomas Eschenhagen

Date : 01/12/2003
Ehjcardiovascrec

Using RNase protection assays (RPAs) RGS2, 3L, 3S, 4, 5 and 6 were identified in the myocardium from terminally failing human hearts with dilated (DCM, n = 22) or ischemic (ICM, n = 18) ...

Cardiovascular Research, Original Article, Clemens Mittmann, Chin Hee Chung, Grit Höppner, Christina Michalek, Monika Nose, Christian Schüler, Antje Schuh, Thomas Eschenhagen, Joachim Weil, ...

Date : 01/09/2002
Ehjcardiovascrec

Abstract Objective: Increased levels of inhibitory G proteins have been observed in heart failure, but their physiological relevance in mediating the reduced β-adrenergic response is largely ...

Cardiovascular Research, Original Article, Paul M.L Janssen, Wolfgang Schillinger, J.Kevin Donahue, Oliver Zeitz, Shahriyar Emami, Stephan E Lehnart, Joachim Weil, Thomas Eschenhagen, Gerd Hasenfuss, ...

Date : 01/08/2002