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Abstract Objective: Based on currently available clinical evidence, we should use high-dose angiotensin converting enzyme inhibitor (ACE-I) for patients with acute myocardial infarction (MI), ...

Cardiovascular Research, Original Article, Tadashi Sugie, Yutaka Kagaya, Morihiko Takeda, Hirokazu Yahagi, Chikako Takahashi, Jun Takahashi, Mototsugu Ninomiya, Jun Watanabe, Ryo Ichinohasama, ...

Date : 01/06/2003 Item size : 295175 bytes

In this context, the position of SMADs in the diseased heart is particularly interesting because, besides their well-known fibrotic effects, increasing evidence demonstrates direct action of SMADs on ...

Cardiovascular Research, Review, Gerhild Euler-Taimor, Jacqueline Heger

Date : 01/01/2006 Item size : 427453 bytes

[...]pathological hypertrophy serves as an independent risk factor for serious cardiovascular diseases such as heart failure. With a view to developing therapeutics for this condition, molecular ...

Cardiovascular Research, INVITED EDITORIALS, Yuichi Ikeda, Eiki Takimoto, Issei Komuro

Date : 15/07/2015 Item size : 174100 bytes

Some of them, including the interleukin (IL)-6 family of cytokines, have been implicated in cardioprotection, cardiac hypertrophy, inflammation, and heart failure via activation of the Janus kinase ...

Cardiovascular Research, Editorial, Jianjian Shi, Lei Wei

Date : 01/12/2012 Item size : 183175 bytes

Abstract Objective: To assess the long-term efficacy of vasopressin (AVP) V1a and V2 receptor blockade with conivaptan, alone and in combination with angiotensin converting enzyme (ACE) inhibition on ...

Cardiovascular Research, Original Article, Mareo Naitoh, John Risvanis, Leanne C. Balding, Colin I. Johnston, Louise M. Burrell

Date : 01/04/2002 Item size : 257113 bytes

Long-term treatment with neutral endopeptidase inhibitor improves cardiac function and reduces natriuretic peptides in rats with chronic heart failure Abstract Objective: Increased secretion of ...

Cardiovascular Research, Original Article, Toshiyuki Maki, Yoshihisa Nasa, Fuminari Yamaguchi, Hiroyuki Yoshida, Masaya Mori, Taku Takada, Eriko Horikawa, Kaori Okano, Satoshi Takeo

Date : 15/08/2001 Item size : 284680 bytes

An expanding body of evidence indicates that certain dietary patterns can influence cardiovascular health and primary prevention of CVD by modifying risk factors such as obesity, dyslipidemia, and ...

Cardiovascular Research, Editorial, Claudio Napoli, William C. Stanley, Louis J. Ignarro

Date : 15/01/2007 Item size : 226859 bytes

In adults, EPO is produced primarily in the kidney via an oxygen-sensing mechanism and stimulates erythroid progenitors in the bone marrow to increase red blood cell mass. The therapeutic relevance ...

Cardiovascular Research, Editorial, Qingping Feng

Date : 01/09/2006 Item size : 169639 bytes

Whether this also holds for patients with chronic heart failure is at present unsettled, but obviously, these patients would benefit most from sinus rhythm since with restoration and maintenance of ...

Cardiovascular Research, Editorial, Isabelle C. Van Gelder

Date : 01/04/2007 Item size : 171177 bytes

Despite major progress in the pharmacological management of congestive heart failure (CHF), life expectancy of patients suffering from CHF remains low [1]. Progress in the treatment of CHF ...

Cardiovascular Research, Editorial, Stéphane Baudet

Date : 01/02/2005 Item size : 164287 bytes