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Ehjcardiovascrec

Two of the most important regulatory factors in this regard are Ca2+ and ADP,47 whose communication between different organelles and/or compartments within cardiac myocytes is organized by ...

Cardiovascular Research, SPOTLIGHT REVIEWS: SPOTLIGHT ON T-TUBULES AND RYANODINE RECEPTOR MICRODOMAIN SIGNALLING IN CARDIAC HYPERTROPHY AND FAILURE, Michael Kohlhaas, Christoph Maack

Date : 01/05/2013 Item size : 513802 bytes
Ehjcardiovascrec

Pharmacological studies have established that a blockade of the RAS at the level of the angiotensin-converting enzyme (ACE) or the AT1-receptor ameliorates the remodeling process of the heart and ...

Cardiovascular Research, Review, Kai C Wollert, Helmut Drexler

Date : 01/09/1999 Item size : 591071 bytes
Ehjcardiovascrec

Mitochondria have been implicated in the loss of cells in various cardiac pathologies, including ischaemia/reperfusion injury, cardiomyopathy, and congestive heart failure. The strategic positioning ...

Cardiovascular Research, Review, Åsa B. Gustafsson, Roberta A. Gottlieb

Date : 15/01/2008 Item size : 598788 bytes
Ehjcardiovascrec

[...]compensatory mechanisms included LV hypertrophy, LV chamber dilation, and enhanced and sustained activity of the sympathetic nervous system and reninangiotensin system [36]. The notion that ...

Cardiovascular Research, Review, Hani N. Sabbah

Date : 01/02/2000 Item size : 422731 bytes
Ehjcardiovascrec

Abstract Atrial natriuretic peptide (ANP) and brain (B-type) natriuretic peptide (BNP) are circulating hormones of cardiac origin that play an important role in the regulation of intravascular blood ...

Cardiovascular Research, Review, Toshio Nishikimi, Nobuyo Maeda, Hiroaki Matsuoka

Date : 01/02/2006 Item size : 426294 bytes
Ehjcardiovascrec

[...]oxidative stress and mtDNA damage are good therapeutic targets. Consistent with alterations in mtDNA, the decrease in mitochondrial function was also prevented. [...]the activation of Prx-3 or ...

Cardiovascular Research, Review, Hiroyuki Tsutsui, Shintaro Kinugawa, Shouji Matsushima

Date : 15/02/2009 Item size : 443610 bytes
Ehjcardiovascrec

Abstract Objective: The cardiac ankyrin repeat protein (CARP), a nuclear transcription co-factor that negatively regulates cardiac gene expression, is increased in human heart failure and in animal ...

Cardiovascular Research, Original Article, Oliver Zolk, Michael Marx, Elmar Jäckel, Ali El-Armouche, Thomas Eschenhagen

Date : 01/09/2003 Item size : 258892 bytes
Ehjcardiovascrec

Abstract Proper contractile function of the heart depends on intact excitationcontraction processes and ion homeostasis of the myocytes. While altered Ca2+-homeostasis has been demonstrated in ...

Cardiovascular Research, Review, Burkert Pieske, Steven R Houser

Date : 15/03/2003 Item size : 469474 bytes
Ehjcardiovascrec

In response to haemodynamic overload under pathological conditions such as hypertension, valvular heart disease, and myocardial infarction, the heart undergoes hypertrophic growth by increasing cell ...

Cardiovascular Research, Editorial, Hiroshi Akazawa, Issei Komuro

Date : 01/04/2014 Item size : 180626 bytes
Ehjcardiovascrec

Introduction Congestive heart failure (CHF) is the leading cause of death in developed countries. Thereby, a better understanding of the cellular and molecular basis of the altered contractility of ...

Cardiovascular Research, Editorial, Stéphane Hatem

Date : 01/04/2004 Item size : 191652 bytes