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The goal of this study was to analyse current changes during the late decompensated phase of heart disease induced by coronary ligation and to compare them in various heart regions. AbbreviationsCm, ...

Cardiovascular Research, Original Article, Franck Aimond, Julio L Alvarez, Jean-Michel Rauzier, Paco Lorente, Guy Vassort

Date : 01/05/1999 Item size : 318228 bytes

Pharmacological studies have established that a blockade of the RAS at the level of the angiotensin-converting enzyme (ACE) or the AT1-receptor ameliorates the remodeling process of the heart and ...

Cardiovascular Research, Review, Kai C Wollert, Helmut Drexler

Date : 01/09/1999 Item size : 591071 bytes

[...]nucleoporin (Nup) p62 was increased in ICM (80%) and DCM (109%) (P < 0.001 and P = 0.024). Introduction Heart failure (HF) has been associated with changes in glycolytic enzymes, mitochondria, ...

Cardiovascular Research, Original Article, Raquel Cortés, Esther Roselló-Lletí, Miguel Rivera, Luis Martínez-Dolz, Antonio Salvador, Inmaculada Azorín, Manuel Portolés

Date : 01/02/2010 Item size : 276957 bytes

Abstract Objective: Implantation of a left ventricular assist device (LVAD) in the failing human heart initiates structural and functional changes termed reverse remodeling. Enhanced caveolin ...

Cardiovascular Research, Original Article, Iván P. Uray, John H. Connelly, O.Howard Frazier, Heinrich Taegtmeyer, Peter J.A. Davies

Date : 01/07/2003 Item size : 259861 bytes

Co-immunoprecipitation experiments suggested that physical interactions occurred between DKK3 and ASK1. [...]rescue experiments indicated that, in DKK3 TG mice, the activation of ASK1 using a ...

Cardiovascular Research, Cardiac biology and remodelling, Yan Zhang, Yu Liu, Xue-Hai Zhu, Xiao-Dong Zhang, Ding-Sheng Jiang, Zhou-Yan Bian, Xiao-Fei Zhang, Ke Chen, Xiang Wei, Lu Gao, Li-Hua Zhu, ...

Date : 01/04/2014 Item size : 333905 bytes

Methods: The effect of various preload conditions (2.515 mN) on force development was studied in right ventricular trabeculae carneae from explanted human failing hearts with ischemic cardiomyopathy ...

Cardiovascular Research, Original Article, Joachim Weil, Thomas Eschenhagen, Stefan Hirt, Olaf Magnussen, Clemens Mittmann, Ute Remmers, Hasso Scholz

Date : 01/02/1998 Item size : 278533 bytes

Introduction Congestive heart failure (CHF) is the leading cause of death in developed countries. Thereby, a better understanding of the cellular and molecular basis of the altered contractility of ...

Cardiovascular Research, Editorial, Stéphane Hatem

Date : 01/04/2004 Item size : 191652 bytes

Methods: cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin-dependent protein kinase II (CaM kinase) were characterized initially by DEAE-Sepharose chromatography in hearts from patients with ...

Cardiovascular Research, Original Article, Uwe Kirchhefer, Wilhelm Schmitz, Hasso Scholz, Joachim Neumann

Date : 01/04/1999 Item size : 306575 bytes

Methods: Cooperative effects in isometric force and rate of force redevelopment (Ktr) were studied in single Triton-skinned human cardiomyocytes at various [Ca2+] before and after protein ...

Cardiovascular Research, Original Article, J van der Velden, Z Papp, N.M Boontje, R Zaremba, J.W de Jong, P.M.L Janssen, G Hasenfuss, G.J.M Stienen

Date : 01/02/2003 Item size : 279632 bytes

Reversible activation of nuclear factor-κB in human end-stage heart failure after left ventricular mechanical support Abstract Objective: Left ventricular assist devices (LVAD) have been used to ...

Cardiovascular Research, Original Article, Florian Grabellus, Bodo Levkau, Andrea Sokoll, Hendryk Welp, Christof Schmid, Mario C Deng, Atsushi Takeda, Günter Breithardt, Hideo A Baba

Date : 01/01/2002 Item size : 219901 bytes