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Abstract Objective:: Transforming growth factor (TGF)-β promotes the deposition of extracellular matrix protein and also acts as an anti-inflammatory cytokine. Methods:: Anterior MI was produced ...

Cardiovascular Research, Research Article, Masaki Ikeuchi, Hiroyuki Tsutsui, Tetsuya Shiomi, Hidenori Matsusaka, Shouji Matsushima, Jing Wen, Toru Kubota, Akira Takeshita

Date : 01/12/2004 Item size : 252606 bytes

Abstract Aims Previously, we showed an enhanced excitatory (N-methyl d-aspartate receptor-NR1) and decreased inhibitory neuronal nitric oxide (NO) synthase (nNOS) influence within the paraventricular ...

Cardiovascular Research, Original Article, Neeru M. Sharma, Hong Zheng, Parmender P. Mehta, Yi-Fan Li, Kaushik P. Patel

Date : 01/11/2011 Item size : 307597 bytes

Abstract Objectives: We studied the effects of chronic left coronary artery ligation on cardiac structure and function in the mouse. Methods: Morphometric studies of the left ventricle were ...

Cardiovascular Research, Original Article, Esther Lutgens, Mat J.A.P Daemen, Ebo D de Muinck, Jacques Debets, Peter Leenders, Jos F.M Smits

Date : 01/03/1999 Item size : 224883 bytes

Abstract Background: We, and others, have previously reported a strong correlation between increased inter-ventricular dispersion of repolarization and the occurrence of fatal arrhythmia in animal ...

Cardiovascular Research, Original Article, Sumeet S Chugh, Stacey Whitesel, Mark Turner, Charles T Roberts, Srinivasa R Nagalla

Date : 01/02/2003 Item size : 273658 bytes

Conclusion Our study shows for the first time that Zac1 is down-regulated both at the transcriptional and protein levels upon PreC and PostC in wild-type mice. [...]inactivation of Zac1 in vivo is ...

Cardiovascular Research, ORIGINAL ARTICLES: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Anne Vincent, Gérald Gahide, Catherine Sportouch-Dukhan, Aurélie Covinhes, Alicia ...

Date : 01/05/2012 Item size : 305766 bytes

Cardioprotection by long-term ETA receptor blockade and ACE inhibition in rats with congestive heart failure: mono- versus combination therapy Abstract Objectives: We investigated the effects of ...

Cardiovascular Research, Original Article, Daniela Fraccarollo, Johann Bauersachs, Markus Kellner, Paolo Galuppo, Georg Ertl

Date : 01/04/2002

[...]despite widespread use of PCI, there has been an increase in the prevalence of ischaemic heart failure, which is mainly attributable to the fact that this treatment has not been as successful as ...

Cardiovascular Research, Editorial, Osamu Tsukamoto, Hiroshi Asanuma, Masafumi Kitakaze

Date : 01/12/2015

The purpose of the present study was to determine whether chronic feeding with high-dose dietary creatine prevents the derangement of energy metabolism and the development of left ventricular ...

Cardiovascular Research, Original Article, Michael Horn, Helga Remkes, Charlotte Dienesch, Kai Hu, Georg Ertl, Stefan Neubauer

Date : 01/07/1999

Abstract Objective: Myocardial contractility is enhanced in transgenic (TG) mice with cardiac-restricted overexpression of the α1A-adrenergic receptors (α1A-AR). Methods We subjected α1A-TG ...

Cardiovascular Research, Original Article, Xiao-Jun Du, Xiao-Ming Gao, Helen Kiriazis, Xiao-Lei Moore, Ziqiu Ming, Yidan Su, Angela M. Finch, Ross A. Hannan, Anthony M. Dart, Robert M. Graham

Date : 01/09/2006

The aim of this study was to examine the effects of long-term administration of AM on left ventricular (LV) remodeling, hemodynamic and hormonal parameters in a rat model of MI. Results: When ...

Cardiovascular Research, Original Article, Ryosai Nakamura, Johji Kato, Kazuo Kitamura, Hisamitsu Onitsuka, Takuroh Imamura, Kousuke Marutsuka, Yujiro Asada, Kenji Kangawa, Tanenao Eto

Date : 01/12/2002