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Ehjcardiovascrec

[...]the identification of key processes setting off a cascade of detrimental cellular changes, ultimately leading to the development of cardiac failure, is still subject of intense research. The ...

Cardiovascular Research, Review, Marc van Bilsen, Pascal J.H Smeets, Andries J Gilde, Ger J van der Vusse

Date : 01/02/2004 Item size : 428514 bytes
Ehjcardiovascrec

For a detailed consideration of physiological vs. pathological hypertrophy (see Dorn, 2007).], resulting from volume overload-induced cardiomyocyte lengthening, without activation of foetal genes3 ...

Cardiovascular Research, Review, Elizabeth A. Woodcock, Xiao-Jun Du, Melissa E. Reichelt, Robert M. Graham

Date : 01/02/2008 Item size : 499739 bytes
Ehjcardiovascrec

Abstract Objectives: Increasing evidence suggests that left ventricular remodeling is associated with a shift from fatty acid to glucose metabolism for energy production. The aim of this study was ...

Cardiovascular Research, Original Article, Nathalie Rosenblatt-Velin, Christophe Montessuit, Irène Papageorgiou, Jérôme Terrand, René Lerch

Date : 01/12/2001 Item size : 286213 bytes
Ehjcardiovascrec

Basal left ventricular end-diastolic pressure (in mmHg) was reduced in the groups in which cariporide was started 1 week pre (16.0±1.7) or 30 min (12.5±1.1), 3 h (11.8±1.0) and 24 h ...

Cardiovascular Research, Original Article, Heidi Spitznagel, Oliver Chung, Qin-Gui Xia, Birthe Rossius, Sascha Illner, Gunnar Jähnichen, Steffen Sandmann, Alexander Reinecke, Mat J.A.P. Daemen, ...

Date : 01/04/2000 Item size : 271349 bytes
Ehjcardiovascrec

The myocardial extracellular matrix (ECM) plays an important role in maintaining the structural and functional integrity of the heart and is centrally involved in wound repair post-myocardial ...

Cardiovascular Research, Review, Davy Vanhoutte, Mark Schellings, Yigal Pinto, Stephane Heymans

Date : 15/02/2006 Item size : 594416 bytes
Ehjcardiovascrec

Methods: Chronic MI was induced in young adult (3.5 months) and aged (18 months) female SpragueDawley rats by ligation of the left coronary artery. Results: Aged control rats differed from young ...

Cardiovascular Research, Original Article, Alexander Deten, Grit Marx, Wilfried Briest, Hans Christian Volz, Heinz-Gerd Zimmer

Date : 01/05/2005 Item size : 291031 bytes
Ehjcardiovascrec

Pharmacological studies have established that a blockade of the RAS at the level of the angiotensin-converting enzyme (ACE) or the AT1-receptor ameliorates the remodeling process of the heart and ...

Cardiovascular Research, Review, Kai C Wollert, Helmut Drexler

Date : 01/09/1999 Item size : 591071 bytes
Ehjcardiovascrec

Mitochondria have been implicated in the loss of cells in various cardiac pathologies, including ischaemia/reperfusion injury, cardiomyopathy, and congestive heart failure. The strategic positioning ...

Cardiovascular Research, Review, Åsa B. Gustafsson, Roberta A. Gottlieb

Date : 15/01/2008 Item size : 598788 bytes
Ehjcardiovascrec

Methods: MI was induced by permanent ligation of the left coronary artery in male normotensive Wistar rats. At these time points, mean arterial blood pressure (MAP), heart rate (HR), left ...

Cardiovascular Research, Original Article, Steffen Sandmann, Jiang-Yong Min, Achim Meissner, Thomas Unger

Date : 01/10/1999 Item size : 409874 bytes
Ehjcardiovascrec

Abstract Objectives: To assess the phosphorylation of myocardial phospholamban (PLB) and quantify protein levels of PLB and sarco/endoplasmic reticulum Ca2+ ATPase type 2 (SERCA 2) in a rabbit model ...

Cardiovascular Research, Original Article, Susan Currie, Godfrey L. Smith

Date : 01/01/1999 Item size : 286941 bytes