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Methods: Chronic MI was induced in young adult (3.5 months) and aged (18 months) female SpragueDawley rats by ligation of the left coronary artery. Results: Aged control rats differed from young ...

Cardiovascular Research, Original Article, Alexander Deten, Grit Marx, Wilfried Briest, Hans Christian Volz, Heinz-Gerd Zimmer

Date : 01/05/2005 Item size : 291031 bytes

Methods and results The following parameters were evaluated: (i) number of ventricular arrhythmias in resting and stress conditions (restraint test) or after aconitine administration; (ii) cardiac ...

Cardiovascular Research, Original Article, Claudia Colussi, Roberta Berni, Jessica Rosati, Stefania Straino, Serena Vitale, Francesco Spallotta, Silvana Baruffi, Leonardo Bocchi, Francesca Delucchi, ...

Date : 01/07/2010 Item size : 280000 bytes

Abstract Aims Left ventricular hypertrophy is a risk factor for heart failure. Glucose and fatty acid oxidation as well as contractile function ex vivo were assessed in the isolated working heart, ...

Cardiovascular Research, Original Article, Torsten Doenst, Gracjan Pytel, Andrea Schrepper, Paulo Amorim, Gloria Färber, Yasushige Shingu, Friedrich W. Mohr, Michael Schwarzer

Date : 01/06/2010 Item size : 346381 bytes

Serum depletion induces cell loss of rat cardiac fibroblasts and increased expression of extracellular matrix proteins in surviving cells Abstract Objective: Since reduced nutrient supply is one ...

Cardiovascular Research, Original Article, Monika Leicht, Wilfried Briest, Alexander Hölzl, Heinz-Gerd Zimmer

Date : 01/12/2001 Item size : 317964 bytes

Abstract Objective: The purpose of this study was to examine the degree to which mechanical alterations in left ventricular papillary muscles of renal hypertensive-diabetic rat hearts correlate with ...

Cardiovascular Research, Original Article, Francis M Siri, Ashwani Malhotra, Stephen M Factor, Edmund H Sonnenblick, Frederick S Fein

Date : 01/04/1997 Item size : 228355 bytes

Impairment in mitochondrial function is thought to contribute to mechanical dysfunction in numerous cardiac disease states, including heart failure.13 However, the underlying mechanisms for ...

Cardiovascular Research, Original Article, Heiko Bugger, Michael Schwarzer, Dong Chen, Andrea Schrepper, Paulo A. Amorim, Maria Schoepe, T. Dung Nguyen, Friedrich W. Mohr, Oleh Khalimonchuk, Bart C. ...

Date : 15/01/2010

Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat Methods: The descending left coronary artery of male rats (Rattus ...

Cardiovascular Research, Original Article, J.Thomas Peterson, Hua Li, Lisa Dillon, John W. Bryant

Date : 01/05/2000

Results: The infarct groups developed progressive pulmonary hypertension and right ventricular hypertrophy with elevated left ventricular filling pressures (all P<0.01). Congestive heart failure ...

Cardiovascular Research, Original Article, Jean-François Jasmin, Angelino Calderone, Tack-Ki Leung, Louis Villeneuve, Jocelyn Dupuis

Date : 01/06/2003

To gain insights into the pathophysiological role of MR function, we established embryonic stem (ES) cell lines from blastocysts of transgenic mice overexpressing the human MR driven by its proximal ...

Cardiovascular Research, Original Article, Damien Le Menuet, Mathilde Munier, Geri Meduri, Say Viengchareun, Marc Lombès

Date : 01/08/2010

Abstract Aims Nuclear factor-κB (NF-κB) plays a critical role in cell growth and inflammation during the progression of cardiac hypertrophy and heart failure. Introduction Cardiac hypertrophy ...

Cardiovascular Research, Original Article, Sijie Wu, Ran Yin, Rick Ernest, Yuquan Li, Olga Zhelyabovska, Jinwen Luo, Yifeng Yang, Qinglin Yang

Date : 01/10/2009