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Ehjcardiovascrec

[...]chronic activation of Epac1 increases the propensity for ventricular arrhythmia by up-regulation of calmodulin protein. Cardiac Epac2, mostly studied in ventricular cardiomyocytes, is located ...

Cardiovascular Research, Pereira, Laetitia

Date : 01/01/2019 Item size : 152632 bytes
Ehjcardiovascrec

[...]during normal pregnancy in women, the substantial increase in blood volume, metabolism and foetal needs require the cardiovascular system to prompt major adjustments to accommodate the needs of ...

Cardiovascular Research, El Khoury, Nabil, Ross, Jenna L, Long, Valérie, Thibault, Simon, Ethier, Nathalie, Fiset, Céline

Date : 01/10/2018 Item size : 319724 bytes
Ehjcardiovascrec

The related subcellular changes in cardiomyocyte ultrastructure and Ca2+ signalling cause a complex pro-arrhythmic substrate, which is difficult to target with current therapeutic approaches.1 ...

Cardiovascular Research, Dobrev, Dobromir, Fender, Anke C, Wehrens, Xander H T

Date : 01/09/2018 Item size : 148159 bytes
Ehjcardiovascrec

Atrial fibrillation (AF) is the most common arrhythmia, which shows a strong increase in prevalence with age and is associated with substantial morbidity and mortality, with worsening heart failure ...

Cardiovascular Research, Dobrev, Dobromir, Lorenz, Kristina

Date : 01/04/2018 Item size : 161160 bytes
Ehjcardiovascrec

Citation Elliot Shinebourne, Roger White; Cyclic AMP and calcium uptake of the sarcoplasmic reticulum in relation to increased rate of relaxation under the influence of catecholamines, Cardiovascular ...

Cardiovascular Research, Shinebourne, Elliot, White, Roger

Date : 12/01/2018
Ehjcardiovascrec

Citation Elliot Shinebourne, Roger White; Cyclic AMP and calcium uptake of the sarcoplasmic reticulum in relation to increased rate of relaxation under the influence of catecholamines, Cardiovascular ...

Cardiovascular Research, Shinebourne, Elliot, White, Roger

Date : 06/10/2017 Item size : 94996 bytes
Ehjcardiovascrec

During the action potential, Ca2+ entry through L-type Ca2+ channels within the t-tubules triggers the opening of closely apposed ryanodine receptors in the sarcoplasmic reticulum, thus eliciting a ...

Cardiovascular Research, Louch, William E., Nattel, Stanley

Date : 01/07/2017 Item size : 101657 bytes
Ehjcardiovascrec

During the action potential, Ca2+ entry through L-type Ca2+ channels within the t-tubules triggers the opening of closely apposed ryanodine receptors in the sarcoplasmic reticulum, thus eliciting a ...

Cardiovascular Research, Louch, William E., Nattel, Stanley

Date : 01/07/2017 Item size : 100976 bytes
Ehjcardiovascrec

Commentary to Ventricular tachycardia ablation versus escalation of antiarrhythmic drugs by Sapp JL et al., N Engl J. 2016.1 Pharmacological antiarrhythmic strategies are limited due to severe side ...

Cardiovascular Research, Sossalla, Samuel

Date : 01/04/2017
Ehjcardiovascrec

Commentary to Ventricular tachycardia ablation versus escalation of antiarrhythmic drugs by Sapp JL et al., N Engl J. 2016.1 Pharmacological antiarrhythmic strategies are limited due to severe side ...

Cardiovascular Research, Sossalla, Samuel

Date : 01/04/2017 Item size : 112961 bytes