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Ehjcardiovascrec

Aims Loss-of-function mutations in the cytoskeletal protein ankyrin-B (AnkB) cause ventricular tachyarrhythmias in humans. CaMKII inhibition greatly reduced Ca 2+ spark frequency in myocytes from ...

Cardiovascular Research, Popescu, Iuliana, Galice, Samuel, Mohler, Peter J., Despa, Sanda

Date : 01/08/2016 Item size : 122320 bytes
Ehjcardiovascrec

Methods and results We performed optical Ca2+ and membrane potential imaging in ventricular myocytes and intact cardiac muscles as well as surface ECGs on a CPVT mouse model with a mutation in ...

Cardiovascular Research, Radwański, Przemysław B., Brunello, Lucia, Veeraraghavan, Rengasayee, Ho, Hsiang-Ting, Lou, Qing, Makara, Michael A., Belevych, Andriy E., Anghelescu, Mircea, Priori, ...

Date : 01/04/2015
Ehjcardiovascrec

Global activities of the major phosphatases PP1 and PP2A were similar in AnkB +/ and WT hearts, while CaMKII autophosphorylation, a marker of CaMKII activation, was increased in AnkB +/ ...

Cardiovascular Research, Popescu, Iuliana, Galice, Samuel, Mohler, Peter J., Despa, Sanda

Date : 01/08/2016
Ehjcardiovascrec

Methods and results We performed optical Ca2+ and membrane potential imaging in ventricular myocytes and intact cardiac muscles as well as surface ECGs on a CPVT mouse model with a mutation in ...

Cardiovascular Research, Radwański, Przemysław B., Brunello, Lucia, Veeraraghavan, Rengasayee, Ho, Hsiang-Ting, Lou, Qing, Makara, Michael A., Belevych, Andriy E., Anghelescu, Mircea, Priori, ...

Date : 01/04/2015 Item size : 448790 bytes
Ehjcardiovascrec

Global activities of the major phosphatases PP1 and PP2A were similar in AnkB +/ and WT hearts, while CaMKII autophosphorylation, a marker of CaMKII activation, was increased in AnkB +/ ...

Cardiovascular Research, Popescu, Iuliana, Galice, Samuel, Mohler, Peter J., Despa, Sanda

Date : 01/08/2016 Item size : 322470 bytes